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Panelists discuss how roflumilast foam, though newly approved for scalp psoriasis, is already showing promise off-label for conditions such as seborrheic dermatitis and nail psoriasis, thanks to its well-tolerated, alcohol- and propylene glycol–free vehicle that improves patient comfort, adherence, and expands topical options for difficult-to-treat areas—potentially reducing reliance on systemic therapies.

Panelists discuss how the recent FDA approval of roflumilast foam for scalp psoriasis represents a significant advancement, combining strong efficacy with a gentle, moisturizing vehicle that enhances tolerability and adherence across diverse hair types and skin tones while offering a steroid-sparing option free from common adverse effects such as hypopigmentation.

Panelists discuss how safety and tolerability are key advantages of newer topical psoriasis treatments such as tapinarof and roflumilast, which avoid many steroid-related risks such as hypothalamic-pituitary-adrenal (HPA) axis suppression and skin thinning, cause minimal irritation, and have favorable real-world profiles that support their use as effective, long-term, steroid-sparing therapies.

An expert discusses the shift in acne treatment from broad-spectrum antibiotics to targeted and nonantibiotic therapies, emphasizing microbiome preservation, resistance reduction, and personalized patient care.