Actinic Keratosis

Australian researchers found 5-FU to be the cheapest AK treatment, compared to imiquimod and MAL-photodynamic therapy.

The novel drug demonstrated tolerability for AK treatment when applied to a field of 100 cm2 of the face or scalp.

The expanded dosage aims to provide healthcare providers with greater flexibility in treating larger or multiple areas affected by AK.

A recent study indicated that 43.3% of lesions achieved a high efficacy score following Alexandrite laser therapy.

One hundred patients with AK rated their therapies with the TSQM and Likert scale, and shared their treatment needs regarding goals, cost, type, duration, and location.

Data from numerous studies identified fluorouracil 5% as ranking the most effective across 3 outcomes.

Biofrontera's red light source is approved for use in combination with aminolevulinic acid hydrochloride (Ameluz) topical gel, 10%.

Phase 3 clinical trial results showed that the safety and tolerability profiles were consistent with those observed in the original pivotal trials.

A study revealed that patients with actinic keratosis reported feeling more pain during red light PDT compared to simulated daylight PDT.

Researchers examined local skin reactions of a topical gel inhibiting cytosolic phospholipase A2 both in-clinic and remotely.

An increased number of tubes of aminolevulinic acid hydrochloride 10% will help patients who have actinic keratosis over large surface areas.

Online patient recruitment methods were effective in a proof-of-concept trial involving patients with low-grade AK.

The study explored the use of the ointment in an area of 100 cm squared.

The analyses were published in the Journal of the European Academy of Dermatology and Venereology.

ChatGPT shows promise in dermatology but needs improvement in accuracy and conciseness for reliable clinical use, according to a study evaluating its performance in actinic keratosis management.

The survey conducted by Almirall included participants in the US and Europe.

As few as 90% of study participants without visible actinic keratosis lesions displayed inflammatory reactions indicative of the presence of subclinical AK lesions.

Investigators noted that there was not a marked increase, however, in keratinocyte skin carcinomas.

Five days of treatment with the topical therapy measurably improved symptoms and emotional/functional impact for patients with actinic keratosis at week 8.

A poster presentation from SBS 2023 reviewed the clinician satisfaction of tirbanibulin for the treatment of actinic keratosis.

The human microbiota and its involvement in human health and disease has been emphasized in recent years. Now, researchers have begun to explore whether a patient’s unique microbiota may influence skin cancer risk and response to therapy.

A recent study evaluated reflective confocal microscopy for actinic keratosis treated with 5-aminolevulinic acid photodynamic therapy.

A study investigated pulsed dye laser-mediated photodynamic therapy compared to conventional PDT for actinic keratosis.

A recent study aimed to examine daylight photodynamic therapy vs cryosurgery for the prevention of actinic keratoses in photodamaged facial skin.

In this study, researchers aim to find the long-term improvements on photoaging after ALA-PDT for AK.

Brian Berman, MD, PhD, maps the root causes, prevention strategies, and latest treatments for this widespread precancer at 2021 Fall Clinical Dermatology Conference for PAs & NPs.

A recent study examines the role of a vegan or omnivore diet on photodynamic therapy for actinic keratosis.

Researchers examine whether daylight PDT is less painful but equally as effective as conventional PDT as treatment for actinic keratosis.

A review of the American Academy of Dermatology guidelines and current treatment improvements for actinic keratosis were discussed during a presentation at Maui Derm NP+PA Fall 2021.

Potential game-changers in the pipeline and newly FDA-approved treatments were highlighted in an overview of new drugs to watch at Maui Derm NP+PA Fall 2021 meeting.