Expert Perspectives

In this Expert Perspectives video series, Michael Payette, MD, MBA; Adam Friedman, MD; Andrew Blauvelt, MD, MBA; James Song, MD; and Linda Stein Gold, MD, discuss the expanding role of oral therapies in the management of plaque psoriasis, with a focus on icotrokinra, the newest targeted oral option. The experts review which patients are best suited to an oral agent, considering disease features, comorbidities such as psoriatic arthritis, and patient priorities, and they examine how new evidence, including head-to-head, indirect, and pooled analyses, should inform clinical decision-making. They also explore the evolving understanding of durable response and share practical strategies for sustaining oral therapy in real-world practice.

In this Expert Perspectives video series, Joshua Zeichner, MD, discusses the clinical presentation and evolving treatment landscape of androgenetic alopecia, or male pattern hair loss. He reviews early signs clinicians should recognize, the condition’s potential impact on patients’ emotional well-being and quality of life, and the challenges patients face when navigating misinformation and over-the-counter hair loss products. Zeichner also explores ongoing unmet needs in androgenetic alopecia and emerging innovations in hair loss biology, with a focus on topical clascoterone 5% solution. Drawing on positive 12-month phase 3 data, he discusses the efficacy and safety findings for clascoterone and explains how its mechanism of androgen receptor inhibition may address the underlying biology of androgenetic alopecia and potentially expand future treatment options for patients.

In this Expert Perspectives video series, Elizabeth A. Buzney, MD, provides a comprehensive clinical resource for dermatologists navigating erythropoietic protoporphyria (EPP). Buzney covers the dermatologic manifestations of EPP and the hallmark phototoxic pain that should raise immediate diagnostic suspicion, explains how EPP-related photosensitivity differs from other photodermatoses, and addresses the consequences of delayed diagnosis. She also reviews the mechanism, long-term safety profile, and real-world prescribing considerations for afamelanotide.

April Armstrong, MD, MPH, highlights a major shift in psoriasis care by emphasizing its systemic nature and the move toward earlier, more proactive treatment with advanced oral therapies. It shows how next-generation TYK2 inhibitors, particularly envudeucitinib, are delivering biologic-level efficacy, rapid symptom relief, and meaningful quality-of-life improvements while maintaining the convenience of oral treatment.

Michael O'Donoghue, MD; Todd Schlesinger, MD; Anthony Rossi, MD; and Neal Bhatia, MD, provide an overview of photodynamic therapy (PDT) optimization for actinic keratoses and superficial basal cell carcinoma, including evidence-based pretreatment and debridement strategies, CPT coding considerations, workflow integration, red-light–based PDT differentiation, and more.

Omar Noor, MD, reviews the mechanistic and diagnostic nuances of chronic hand eczema and shares practical insights on when he turns to delgocitinib cream, including its efficacy, patient experience, and minimal systemic absorption.

Lindsay Ackerman, MD; Michael Lewitt, MD; and Marc Serota, MD, discuss the use of topical therapies for vitiligo. The panelists review efficacy and safety data, special considerations for pediatric patients, and practical strategies to support repigmentation in difficult-to-treat areas.

Shanna Miranti, MPAS, PA-C; Tina Bhutani, MD; and Walter Liszewksi, MD, discuss the burden of moderate to severe pediatric atopic dermatitis (AD) on both patients and their caregivers. The panelists review the 3 available non-steroidal topicals, their itch data, skin clearance rates, and how topicals and systemics can be combined to best support pediatric patients.

This news content has been independently developed and is not endorsed by the American Academy of Dermatology:

Lisa Swanson, MD, FAAD; Aaron Farberg, MD; James Song, MD, FAAD; Alexandra Golant, MD, and Jennifer Soung, MD, discuss how, advancing pediatric atopic dermatitis management faces challenges of treatment adherence and limited pediatric-specific therapies. Recent innovations include targeted biologics, patient education tools, and multidisciplinary approaches. Future directions emphasize personalized medicine, barrier repair technologies, and improved quality-of-life assessment tools tailored to children's unique needs.

Medical experts Karan Lal, DO, MS, FAAD; Cheri Frey, MD; Corey Hartman, MD, FAAD; Sophia Reid, MD, and Cheryl Burgess, MD, explain how laser therapy can effectively treat chronic skin conditions through targeted light exposure while emphasizing the importance of customized treatment protocols and combination approaches for optimal patient outcomes.

Gina Mangin, MPAS, PA-C, discusses how evaluating atopic dermatitis treatment success requires a comprehensive approach that combines developing personalized treatment plans, identifying individual triggers, and measuring outcomes through both clinical assessments and patient-reported improvements in symptoms and quality of life.

Robert Casquejo, PA-C; Karan Lal, DO, MS, FAAD; Lisa Weiss, MMSc, PA-C; James Song, MD, FAAD, and Douglas DiRuggiero, examine how atopic dermatitis affects diverse patient populations through varied clinical presentations, psychosocial burdens, and health care delivery methods, including telemedicine.

Andrew Alexis, MD, MPH; Karan Lal, DO, MS, FAAD; James Song, MD; Lisa Swanson, MD, and Lisa Swanson, MD, address vitiligo management across adult and pediatric populations, examining treatment strategies, psychological support, emerging therapies like JAK inhibitors, and the critical importance of individualized care plans that consider disease characteristics, age-specific needs, and family education.

Aaron Farberg, MD, discusses how red light therapy’s diverse applications in wound healing and aesthetic dermatology offer a noninvasive treatment option with promising outcomes across various medical and cosmetic fields.

Five experts delve into the multifaceted aspects of pediatric atopic dermatitis care including demographic variances to long-term safety and efficacy, comparative analyses, key takeaways from recent research, personalized approaches, and future research directions. Discover clinical insights into the role of ruxolitinib in addressing critical challenges and enhancing patient outcomes.

This series delves into the multifaceted landscape of atopic dermatitis (AD) care and treatment. Through interviews with 4 leading dermatologists, this series explores key benchmarks, emerging trends, personalized medicine approaches, long-term safety considerations, and the integration of novel therapies in the management of AD.

An expert in dermatology introduces a video series program exploring cutting-edge treatments at the forefront of atopic dermatitis management, exploring innovative insights and research that will redefine dermatological care.

Experts in dermatology discuss key highlights, updates, and take-aways from the 2023 Science of Skincare Summit.

Experts in dermatology discuss hot topics in skin care from AAD 2023 relating to skin renewal, photoprotection in patients with skin of color, next generation cleansing technologies, and the use of over the counter and prescription acne products.

Experts in dermatology discuss the practical and clinical considerations in the management of Generalized Pustular Psoriasis; highlighting a recent treatment approval.