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A panelist presents a case of severe, chronic facial seborrheic dermatitis in a young man, highlighting diagnostic challenges and emotional impact, and illustrating how daily use of a phosphodiesterase-4 (PDE4) inhibitor foam led to near-clearance and symptom relief by 8 weeks, underscoring the therapy’s effectiveness, safety, and adaptability to patient preferences.

Panelists discuss the structure and function of the skin barrier, highlighting key components like filaggrin and aquaporins, and emphasizing the need to protect against both environmental and lifestyle-related stressors—collectively known as the exposome—to maintain hydration and support long-term skin health.

A panelist presents a case of severe seborrheic dermatitis in a young man with facial and scalp involvement, demonstrating how a once-daily, foam-based phosphodiesterase-4 (PDE4) inhibitor provided rapid, complete clearance and itch relief, highlighting the importance of efficacy, cosmetic acceptability, and quality-of-life considerations in treatment selection.

Panelists discuss how the availability of both roflumilast foam and cream allows for personalized, preference-driven treatment plans that enhance adherence while streamlined access strategies and improved topical efficacy are reshaping the role of nonsteroidal agents in psoriasis care, extending their use beyond mild disease to special sites and even as systemic-sparing options.