The Weekly Roundup: October 6-10

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FDA Expands Roflumilast Access to Children as Young as Age 2

The approval represents the sixth FDA authorization for roflumilast since 2022.

Uniting Dermatology and Oncology During Breast Cancer Awareness Month

Explore the vital role of dermatology in breast cancer care, from early detection to managing skin issues related to treatment and radiation.

Neuroimmunology and Dermatology: The Future of Process-Based Medicine

Brian Kim, MD, FAAD, explores the transformative role of neuroimmunology in dermatology, urging a shift towards systems-level therapeutic strategies.

Extended-Release Minoxidil Shows Promise in AGA

The investigational extended-release tablet maintained therapeutic plasma levels while avoiding peaks linked to cardiovascular risk.

Sitryx Advances Novel Oral Therapy SYX-5219 for Atopic Dermatitis with FDA IND Clearance

Sitryx Therapeutics advances SYX-5219 for moderate to severe AD, aiming for a first-in-class oral treatment with potential for lasting disease remission.

Pan-JAK Inhibition Proves Effective Across CHE Subtypes

Delgocitinib showed consistent efficacy in atopic, irritant, allergic, and hyperkeratotic forms of chronic hand eczema in pooled trial data.

Breast Cancer Awareness in Dermatology

Dermatologists play a crucial role in breast cancer care, enhancing patient outcomes through early detection and innovative research on keratin-targeting therapies.

IPC Brings Clarity to Topical Therapy Failure

Discover the latest IPC consensus on psoriasis severity reclassification, enhancing treatment strategies for better patient outcomes and quality of life.

How LP-10 Could Transform Treatment for Oral Lichen Planus

Lipella Pharmaceuticals' LP-10 shows promise as a targeted treatment for OLP, offering safety and efficacy in recent trials, according to Michael Chancellor, MD.

Evaluating Dose-Dependent Skin Changes from Long-Term Isotretinoin Therapy, Including CHE

New research highlights the link between isotretinoin dosage and increased chronic hand eczema, emphasizing the need for careful monitoring during acne treatment.

APG777 May Ease Burden on Patients With AD

The biologic’s less frequent injections could ease logistical and emotional strain for patients with atopic dermatitis and their families.

Journal Digest: October 8, 2025

This review of the latest dermatologic studies highlights new research on mitigating irritation from 0.1% retinol, OTC therapies for alopecia, the perception of skin lesions by HCPs in the delivery room, and more.

Vitiligo Disease Duration Linked to Depression Severity

Findings suggest that physical activity alone may not meet the psychosocial needs of vitiligo patients, emphasizing the need for targeted mental health care.

STRATA Excimer Laser and JAK Inhibitors Deliver Superior Vitiligo Repigmentation

A new trial reveals that combining Excimer laser with JAK inhibitors significantly enhances vitiligo treatment outcomes, ensuring safety and durability.

Eichenfield Highlights Clinical Value of Roflumilast Cream for Pediatric AD

The FDA has approved roflumilast 0.05% cream for atopic dermatitis in children aged 2 years and older, extending its use to a critical pediatric population.

Tailoring Psoriasis Therapy for Adherence, Comorbidities, and Hard-to-Treat Areas

Explore real-world psoriasis management insights from Anthony Nuara, MD, PhD, focusing on patient-centered approaches and innovative treatments like tildrakizumab.

Dermatology Steps Forward in Onco-Skin Management

Radiation dermatitis significantly affects breast cancer patients, impacting quality of life and treatment. Discover effective prevention and management strategies.

Unveiling the Psychosocial Impact and Lifestyle Factors Associated with Rosacea in China

New research highlights the psychosocial impact of rosacea on Chinese patients, linking lifestyle factors and comorbidities to quality of life.

Ritlecitinib Shows Early Efficacy in Alopecia Subtypes

A late-breaking EADV presentation revealed that ritlecitinib significantly improved outcomes in patients with multiple forms of scarring alopecia.

Boxed Warning or Boxed In? Brownstone Explains FDA Risk Labels at PDPA 2025

Brownstone’s PDPA session explores how class labeling and insufficient data can mislead clinicians and alarm patients unnecessarily.

Amy Lewis, MD, on Glo2Facial's Multi-Technology Approach and the Power of Internal Oxygenation

Discover how the Glo2Facial revolutionizes aesthetic dermatology with innovative skin oxygenation and customizable treatments for radiant, youthful skin.

Q&A: Redefining Clinical Trials Through Community-Based Dermatology

Jorge Garcia-Zuazaga, MD, MBA, FAAD, FACMS, discusses Apex Skin’s mission to make research more representative and accessible through integrated, multisite dermatology practices.

Unseen Delays: How Psoriasis Disrupts the Wound Healing Landscape

Psoriasis complicates wound healing due to systemic inflammation, affecting recovery and requiring tailored clinical approaches for optimal patient outcomes.

Hyaluronic–Succinic Mesotherapy Cuts Rosacea Redness by 80 %

Discover how mesotherapy with hyaluronic and succinic acids significantly improves rosacea symptoms, offering a cost-effective adjunct therapy option.

Upadacitinib Shows Promise in Refractory Lichen Amyloidosis

Selective JAK1 inhibition with upadacitinib may offer a fast-acting, steroid-sparing option for refractory lichen amyloidosis by interrupting IL-31–mediated itch and the itch–scratch cycle.

Early Intervention with Ixekizumab Yields Superior PASI Responses

A study reveals ixekizumab's effectiveness in treating mild to moderate plaque psoriasis, showing superior PASI responses and improved long-term outcomes.

Building Patient Rapport with Modern Regenerative Aesthetic Devices

Amy Lewis, MD, integrates Glo2Facial into her practice to enhance patient relationships and promote early skin health through innovative aesthetic treatments.