The Weekly Roundup: December 1-5

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Baricitinib, Ritlecitinib, Deuruxolitinib: Comparative Efficacy in AA

Bayesian network meta-analysis and MAIC consistently favored deuruxolitinib over baricitinib and ritlecitinib for SALT ≤10 and ≤20 endpoints.

Q&A: Optimizing Copper Peptide Through Next-Generation Delivery

Nayan Patel, PharmD, is revolutionizing skin rejuvenation with advanced delivery technology of GHK-Cu for youthful vitality.

Patrick Burnett, MD, PhD, Outlines Arcutis' Pediatric Strategy for Roflumilast in AD and Psoriasis

Arcutis is advancing pediatric dermatology with innovative, steroid-sparing treatments for atopic dermatitis and plaque psoriasis, enhancing care for young patients.

Clinical Guidance Needed as Patients Turn to Tallow for Skin Conditions

While individual fatty acids in tallow have known biological effects, their combined impact in whole tallow remains uncertain.

Q&A: Dermatologists' Critical Role in Managing Cutaneous Toxicities in Lung Cancer Therapy

Mondana Ghias, MD, FAAD, offers strategies for dermatologists in managing skin reactions from lung cancer treatments to enhance patient care and quality of life.

Arcutis’ 2026 Pipeline Expansion into Vitiligo, HS, and Systemic Biologics

Patrick Burnett, MD, PhD, of Arcutis, explores new treatments for vitiligo and hidradenitis suppurativa, while advancing systemic biologics for atopic dermatitis by 2026.

Giving Tuesday: Impactful Organizations to Support

Support vital dermatology organizations this Giving Tuesday and beyond to enhance patient care, drive research, and foster community.

Experts Highlight Earlier, Smarter HS Treatment Strategies

Participants agreed that HS is rarely controlled with monotherapy and often requires coordinated multimodal care.

Lymphir Launches in US as First New Systemic for CTCL in Over 7 Years

Citius Oncology’s IL-2 receptor–directed fusion protein offers rapid responses and pruritus improvement for relapsed or refractory stage I–III CTCL.

Syrian Study Confirms Isotretinoin’s Effectiveness in Acne Treatment

However, over half of the patients reported experiencing psychological symptoms such as mood changes and depression during treatment.

Journal Digest: December 3, 2025

This review of the latest dermatologic studies includes a new instrument to measure QoL in pediatric alopecia, BTX-A in patients with recessive dystrophic epidermolysis bullosa, and more.

Phase 1b Trial Completed for Potential HS Therapy NAV-240

Navigator Medicines advances NAV-240, a promising bispecific antibody for HS, targeting dual pathways for enhanced treatment efficacy.

Hair Relaxers Tied to Higher Risk of Non-Reproductive Cancers, According to NIH Study

The study provides new evidence beyond previously established associations with breast, ovarian, and uterine cancers.

Natural Fatty Acids Offer Hair Loss Relief

Discover how a proprietary extract from saw palmetto promotes hair growth and reduces thinning in adults, offering a safe alternative to traditional treatments.

How Clinicians are Navigating JAK Inhibitors and Patient Expectations in Alopecia Areata

Arash Mostaghimi, MD, MPH, FAAD, and experts discuss evolving treatment standards for alopecia areata, focusing on JAK inhibitors, patient-centered care, and future therapeutic innovations.

Reviewing Type 2 Inflammation Through a Different Lens

At the Horizons in Advanced Practice meeting, Omar Noor, MD, led NP and PA attendees through 3 complex cases of atopic dermatitis, prurigo nodularis, and chronic spontaneous urticaria.

Derm Dispatch: What 'Free to Be Me' Means to Tori Spelling and Stella McDermott

Tori Spelling and Stella McDermott share their journey with eczema, promoting the Free to Be Me campaign and discussing innovative treatments like roflumilast.

Clascoterone 5% Delivers Strong Phase 3 Hair-Growth Results

Cosmo Pharmaceuticals reveals promising phase 3 results for clascoterone 5% solution, showing significant hair growth improvement in alopecia.

Dermatology Conferences and Meetings Calendar: December 2025

Dermatology Times has compiled a list of dermatological meetings taking place during the month of December.

Alpha-9 Begins First-in-Human Trial of MC1R-Targeted Radiotherapeutic

Alpha-9 Oncology's A9-3408 trial targets MC1R in advanced melanoma, offering a novel radiotherapeutic approach beyond traditional treatments.

Rethinking Pathogenesis and Severity Assessment in Chronic Hand Eczema

Omar Noor, MD, outlines the complex phenotypes, variable presentations, and functional burdens of chronic hand eczema and explains why a broader JAK-targeted strategy may offer therapeutic advantages.

ICYMI: First Patient Dosed in Global Phase 2 Study of Oral TYK2 Inhibitor Soficitinib for PN

InnoCare Pharma has initiated a global trial for soficitinib, targeting prurigo nodularis, aiming to enhance treatment options for this chronic skin condition.

Treating Postpartum Abdominal Skin Laxity with Bipolar Microneedle Radiofrequency

New study reveals how microneedle radiofrequency technology effectively addresses postpartum abdominal skin laxity, enhancing skin elasticity and patient satisfaction.

Experts See Promise in AI for Atopic Dermatitis Care

Experts explore the integration of AI in atopic dermatitis management, highlighting benefits, risks, and the need for cautious implementation in patient care.

New Analysis Finds Radiofrequency Microneedling Superior for Rosacea Erythema and Patient Satisfaction

Discover the latest insights on laser and energy-based treatments for rosacea, highlighting the effectiveness of radiofrequency microneedling and combination therapies.

Nearly Half of Female Psoriasis Patients Report IPV, Study Finds

A study reveals high rates of intimate partner violence among women with psoriasis, linking it to poorer quality of life and increased PTSD symptoms.