Psoriasis

Alice Gottlieb, MD, PhD, put a spotlight on recent studies and the current psoriasis treatment armamentarium for dermatology clinicians to consider.

The IFPA Forum Roadmap for Asia outlines key advocacy demands and practical strategies to improve psoriatic care throughout the continent.

Artax announced that safety and efficacy data is expected in the second half of the year.

A new study suggests patients with psoriasis may experience exacerbated disease burden waiting to initiate systemic treatment.

Data from the FRONTIER 1 clinical trial were recently published in the New England Journal of Medicine.

The VISIBLE clinical program will create a longitudinal collection of more than 20,000 clinical images across all skin tones.

New evidence identifies factors that may predict which patients with psoriasis will develop psoriatic arthritis.

This article will highlight recently approved psoriasis therapies that will shape the 2024 treatment landscape and provide some exciting updates in the psoriasis management market this coming year and beyond.

A recent retrospective cohort study described drug survival and treatment patterns among patients with newly-diagnosed generalized pustular psoriasis.

When examining Ezra’s skin, you note well-defined erythematous scaly plaques with well-defined, serpiginous, raised borders and yellow crusting on the anterior shins and forearms.

Researchers say that application of these findings in clinical settings could enhance treatment optimization.

Drs Lisa Swanson and Robert J. Casquejo express their optimism for the future of plaque psoriasis management, sharing their vision for expanded treatment approvals in the pediatric population affected by this condition.

Experts in dermatology highlight the crucial role of setting treatment response expectations and stress the need for discussions on managing mild plaque psoriasis, highlighting the utilization of systemic therapies in this context.

Experts in dermatology emphasize the need to consider patients' overall well-being when evaluating the safety profiles of emerging biologic treatments for plaque psoriasis, taking into account the heightened levels of depression and anxiety in individuals with this condition.

George Han, MD, discusses the latest biologic agents for plaque psoriasis, addressing the balance between efficacy and speed of response. Together with Dr. Leon Kircik, they emphasize the significance of comprehensive data for physician confidence and delve into the clinical utilization of these treatments, stressing the importance of baseline laboratory measurements for all prescribed patients.

Leon Kircik, MD, emphasizes the combined use of emerging topical treatments with systemic or biologic medications and the impact of the treatment vehicle on penetration. He also discusses the potential for longer use of steroidal options by reducing active product quantities through better penetrating vehicles and highlights the potential heightened efficacy of newer topical treatments and the gaps they may fill in the management of this condition.

The topical therapy was more effective in patients with psoriasis and AD when compared to a vehicle control cream.

A meta-analysis revealed that a post-operative care routine that involves psychological well-being leads to improved patient outcomes.

Soligenix shared today positive top-line data stemming from the phase 2a clinical trial.

Lisa Swanson, MD, FAAD and Robert J. Casquejo, PA-C discuss the shifting treatment landscape, shedding light on phosphodiesterase inhibitors-4 (PDE4) and comment on why it holds promise as a therapeutic target for immune-mediated diseases.

Drs Lisa Swanson and Robert J. Casquejo elaborate on their treatment selection approach for plaque psoriasis, underscoring the significance of systemic treatments and their proven efficacy in managing this condition.

The BLA submission for DMB-3115 is rooted in phase III multi-regional clinical trials focusing on plaque psoriasis patients. The results demonstrated a high similarity between DMB-3115 and ustekinumab in terms of quality, safety, and efficacy.

While the first ustekinumab biosimilar, Wezlana, was approved in October 2023, a settlement with Johnson & Johnson (J&J) will keep it off the market until 2025, preventing competition, and causing purchasers to pay substantially more for the agent.

Test your knowledge of psoriasis treatment options with our 5-question quiz.

As 2023 comes to a close, Dermatology Times is taking a look back at the studies, therapies, and advances in psoriasis this year.

Most studies involving the treatment of psoriasis do not contain any images of patients, a review finds.

Experts in dermatology delve into patient communication regarding treatment expectations, emphasizing the significance of ongoing follow-up and maintenance practices. They also address the safety, tolerability, and comfortability aspects associated with the use of this novel TYK-2 inhibitor, drawing insights from long-term clinical trial data.

Linda Stein-Gold, MD, Mona Shahriari, MD, and Micheal Cameron, MD, FAAD explore emerging oral treatments for the management of plaque psoriasis, emphasizing the novelty of TYK-2 inhibition. They discuss the unique POETYK trial design, stressing the importance of the inclusion of an active control arm. Lastly, they highlight the clinical efficacy of this novel treatment MOA.

Read the top 10 takeaways from a recent discussion among experts in the management of plaque psoriasis.

Lisa Swanson, MD, FAAD, and Robert Casquejo, PA-C, discuss their preferred treatment approach for plaque psoriasis, which includes PDE4 inhibitors such as apremilast and roflumilast.