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Opinion|Videos|September 20, 2024
Evolution of Plaque Psoriasis Understanding, Pathophysiology, and Treatment Options
Author(s)E. James Song, MD, FAAD
E. James Song, MD, FAAD, provides detailed insights on how our understanding of plaque psoriasis has evolved and the ways that has impacted treatment options and decisions.
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In a retrospective study of 393 patients, 51.9% had at least 1 abnormal LFT during follow-up, but only 1.1% had elevations above 3 times the upper limit of normal.
Patients with plaque psoriasis treated with roflumilast cream or foam reported greater improvements in sexual function and relationships vs vehicle, including those with genital involvement at baseline.
By week 36, combination therapy altered 482 proteins and 467 genes vs 140 and 16 with ixekizumab alone in exploratory TOGETHER-PsO data.
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