July 24th 2024
Margins < 1 mm also do not increase the risk of cutaneous squamous cell carcinoma recurrence risk if the galea aponeurotica is not involved.
PER Skin Summit: Optimizing Diagnosis and Individualizing Management of Hidradenitis Suppurativa
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Community Practice Connections™: 19th Annual International Symposium on Melanoma and Other Cutaneous Malignancies®
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Cases and Conversations™: Applying Best Practices to Prevent Shingles in Your Practice
October 16, 2024
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Expert Illustrations & Commentaries™: A Deeper Look at the Pathogenesis of Hidradenitis Suppurativa (HS)
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Cancer Summaries and Commentaries™: Clinical Updates in Melanoma from Philadelphia
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21st Annual International Symposium on Melanoma and Other Cutaneous Malignancies®
February 8, 2025
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Expert Illustrations & Commentaries™: Picturing the Potential Role of OX40 and OX40L Inhibitors in Atopic Dermatitis
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Hidradenitis Suppurativa (HS): Deepening Foundations of Knowledge in Disease Pathogenesis, Disease Severity Assessment, and Treatment Decision-Making
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Clinical Consultations™: Optimizing Treatment Outcomes for Patients with Generalized Pustular Psoriasis
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Rapid responders may offer clues to optimize immune therapy
July 6th 2015Some patients respond more rapidly to immune therapies like ipilimumab, and clinicians have observed delayed toxicities with prolonged use of checkpoint inhibitors; effective treatments for subtypes of melanoma, such as uveal melanoma, have not yet emerged.
Dinutuximab wins FDA approval for neuroblastoma
March 31st 2015FDA has approved dinutuximab (Unituxin, United Therapeutics) in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of high-risk pediatric neuroblastoma patients who achieve at least a partial response to prior first-line multiagent, multimodality therapy.
Advances in understanding, treating MCC
March 19th 2015Outcomes for patients with Merkel Cell Carcinoma are typically poor and therapeutic options are limited, but advances in understanding the biology of the disease, as well as emerging cutting-edge treatments are expected to improve the outlook, experts say.
Ipilimumab evaluated as adjuvant therapy
March 18th 2015Ipilimumab has been evaluated in the adjuvant setting. One expert predicts that ipilimumab’s positive effect on progression-free survival will translate into improvements in overall survival; however, he cautions that there is a risk:benefit ratio to be weighed.
Cutaneous T-cell lymphoma: Poised for a new treatment paradigm
January 16th 2015Researchers are aiming to better understand the molecular signaling pathways and the immune microenvironment of cutaneous T-cell lymphoma. The use of targeted or mechanism-based therapies may lead to better-understood combinations, higher response rates and better survival.
Gigapixel camera has eye for melanoma
January 12th 2015Whole-body photographic camera developed out of U.S. military surveillance technology may have applications in dermatology. Dermatologists could one day use the camera to take whole-body images in high-risk patients; then, let a computer do the work of analyzing lesions that need attention.
FDA accelerates approval of melanoma drug
January 2nd 2015The Food and Drug Administration has granted accelerated approval to nivolumab (Opdivo, Bristol-Myers Squibb) for the treatment of unresectable or metastatic melanoma and for patients whose disease has progressed following ipilimumab and, if BRAF V600 mutation-positive, a BRAF inhibitor.