New device treats nonmelanoma skin cancer
A new energy-based device delivering ultrafast pulses of high amplitude electrical energy to nonthermally preferentially clear targeted cell rich lesions is proving to be a very useful treatment modality for a number of benign dermatologic lesions.
Systemic antibiotics impact skin microbiota in rosacea patients
A recent study published in the Journal of Clinical Medicine evaluated the changes seen in the skin’s microbiota of patients following antibiotic therapy to elucidate which organisms might play the biggest role in development of rosacea symptoms.
Potential first-line treatment for advanced cutaneous squamous cell carcinoma
The epidermal growth factor (EGFR) inhibitor cetuximab achieved good outcomes in patients with advanced SCC, according to results of a recent study.
Immunotherapy for advanced squamous cell carcinoma
Immunotherapeutic agents have become an important treatment option for patients with advanced squamous cell carcinoma
Mast cells may play key role in rosacea pathogenesis
Mast cells appear to play an intricate role in the pathophysiology of rosacea and could serve as potential targets for future therapies, according to recent study findings.
The future of actinic keratosis treatment
It is estimated that 0.025% to 16% of all actinic keratosis (AK) lesions may progress into invasive SCC per year, and there is still no marker to predict which lesions will progress, according to a recent paper that outlined diagnostic challenges as well as current and pipeline treatment approaches.
Pipeline treatments show promise for acne patients
Hilary E. Baldwin, M.D. discusses advances in acne treatment that have expanded treatment options, allowing physicians to improve outcomes in patients with moderate-to-severe acne.
A paradigm shift in squamous cell carcinoma treatment
Recent advances in systemic therapies have led to the development of PD-1 checkpoint inhibitors, which one expert says may represent a paradigm shift in the treatment and management of patients with locally advanced or metastatic cutaneous squamous cell carcinoma (SCC).
Expert discusses hair loss treatment controversies, concerns
It is important for clinicians to stay abreast with the latest data coming out of trials and individually consult their hair loss patients accordingly on a case by case basis, says this expert.
Targeted therapies for advanced basal cell carcinoma
Continued research has produced a number of targeted therapies that provide hope for patients with this rare but sometimes deadly form of nonmelanoma skin cancer.
Vaccine shows promise in advanced melanoma patients
Positive outcomes with an experimental vaccine provide hope for patients with stage IIB and IIC melanoma.
Standard of care for primary cutaneous melanoma evolves
Though still considered controversial, several evolving treatment and management plans for primary cutaneous melanoma are making their way into the mainstream and challenging more traditional approaches.
Psoriasis guidelines offer management pearls for pediatric patients
New joint AAD-NPF guidelines consider the quality-of-life impact of pediatric psoriasis as well as comorbidity risks in this patient population.
Gene expression profile testing aids skin cancer management
Gene expression profile (GEP) testing outcomes have positively impacted the management decision-making process for cutaneous squamous cell carcinoma (cSCC), according to a recent study.
Topical botanicals prove effective for pediatric atopic dermatitis
A novel cocktail of topically applied botanicals has recently proven useful in the treatment and management of mild-to-moderate atopic dermatitis in children, offering hope for this patient population.
Newer multi-modal approaches to treat keloids
Newer treatment approaches may soon become mainstream in the treatment and management of keloids, one expert says.
Diet may impact squamous cell carcinoma risk
Fruits and vegetables rich in vitamin A appear to play a significant role in helping to decrease the incidental risk of developing squamous cell carcinoma, according to a recent study.
Genetic expression testing still a work in progress for melanoma
One expert believes that clinicians may want to seek a second pathologic opinion for particularly difficult-to-diagnose melanocytic lesions before solely relying on the results of existing molecular assays.
Nanovaccine shows promise for melanoma
A novel nanovaccine has demonstrated efficacy in preventing the development of melanoma in mouse models, according to a recent study.
Technology improves histologic diagnosis in melanoma
Malignant melanoma can mimic many melanocytic lesions and vice versa, making it a difficult diagnosis. As such, accurate diagnosis should be a collaborative effort between clinician and dermatopathologist, says this expert.
Melanoma management perspectives vary
There are many different aspects to the treatment and management of primary melanoma, but clinicians differ on their perceptions of the ideal treatment approach.
IL-4, IL-13 cause scratching in mice
A recent study in experimental mice showed that interleukin-4 and interleukin-13 act as acute pruritogens, supporting the benefit of targeting these cytokines in the therapeutic planning of the patients with pruritus.
Rosacea, breast cancer possibly linked
Patients with rosacea appear to have a significant increase in the risk of breast cancer when compared to those without this skin condition, according to a new study.
Genetics may play role in keloid formation
The formation of keloids may be due to a genetically based switch normalization failure in the remodeling stage of wound healing, says Greg Goodman, M.D. Find out more in this article.
Skin cancer imaging device speeds diagnosis
A new technology based on laser-induced breakdown spectroscopy has demonstrated accuracy in both sensitivity and specificity for discriminating skin cancers from benign lesions, one expert says.
Genetic insights improve tumor classification
Accurately diagnosing some melanocytic neoplasms is challenging because they may fall into a grey area histologically, one expert says. Recent progress in molecular genetics can help dermatopathologists more precisely classify tumors, leading to more appropriate treatment and management choices.
Fat intake linked to skin cancer risk
A recent study investigating the association between dietary fat intake and the development of skin cancers found polyunsaturated fat intake especially omega-6 fat to be modestly and consistently associated with skin cancer risk.
Update: Immunotherapy for melanoma
It is only recently that continued research has led to significant advances in numerous immune-based drugs that can successfully be used in patients with advanced melanoma (stage III and IV).
Hidradenitis suppurativa and Crohn’s disease link
Researchers writing in JAMA Dermatology report that patients diagnosed with hidradenitis suppurativa (HS) are at a higher risk for having or developing Crohn’s disease (CD).
New AAD cSCC treatment guidelines
The new AAD cSCC treatment guidelines highlight alternative therapeutic or preventive treatment options.
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