Ilya Petrou, MD

Articles

Patients with rosacea can get better results by supplementing standard minocycline oral therapy with γ-linolenic acid (GLA), according to findings from a recent study.

GLA Offers Promise as Add-on Therapy to Minocycline 

A recent study found states' Medicare per-beneficiary spending between actinic keratosis and skin cancer differs widely.

Medicare Spending on Skin Cancer, AK Varies Widely

Several systemic therapies are currently available for the treatment of patients with moderate-to-severe psoriasis. Biologics changed the game for treatment. Continued study of and innovation in IL-17 and IL-23 inhibitors promise even better results, but clinicians need to understand each biologic in detail. 

IL-17, IL-23 Inhibitors May Outperform Older Biologics, Oral Therapies

One expert says the action of demodex folliculorum and the composition of the symbiotic microbiota in the skin of patients with rosacea may provide valuable insights into the pathogenesis and pathophysiology of this widespread skin disease.

Pathogens, Microbiota May Impact Rosacea 

Several systemic therapies are available for the treatment of patients with moderate to severe psoriasis. Continued research has further elucidated the immunopathogenesis of the disease, leading to the development of novel biologic agents that are proving to more effectively and safely address moderate to severe psoriatic lesions.

Expanding Line of Therapeutic Agents for Psoriasis 

Recently, PRAME (preferentially expressed antigen in melanoma) immunohistochemical staining has shown its usefulness in distinguishing benign from malignant melanocytic cell populations, offering another color to the canvas in the quest for a more definitive diagnosis of melanoma.  

Utility of PRAME staining in identifying malignant transformation of melanocytic nevi

While Mohs micrographic surgery is well established as a safe and effective therapeutic modality in adult patients, it is not as commonly used in pediatric populations. There are unique challenges to performing Mohs surgery on pediatric patients, especially with patient cooperation. Multidisciplinary planning may be needed.

Mohs micrographic presents challenges in kids 

Investigators of a recent study found a 40-gene expression profile (40-GEP) test helps improve identification of high risk for metastatic disease in patients with cutaneous squamous cell carcinoma (cSCC).

Gene expression profile test predicts metastatic risk

Researchers conducted a critical appraisal of a systematic review of six different smartphone apps and found little evidence that they are effective in self-monitoring or skin cancer detection, according to a recent study. 

Smartphone apps not effective in skin cancer risk 

Dupilumab and JAK inhibitors are leading the way in atopic dermatitis treatment, but there are numerous clinical trials of both new biologics and new small molecule drugs, and future treatment regimens likely will utilize both. 