
Day 2 Recap: AAD 2026
Key Takeaways
- Pediatric atopic dermatitis outcomes with nemolizumab included high EASI-90 achievement and rapid itch reduction, supporting IL-31 pathway targeting for pruritus-dominant disease.
- Topical roflumilast 0.05% generated efficacy signals with favorable tolerability in infantile atopic dermatitis, reinforcing PDE4 inhibition as a steroid-sparing option in very young patients.
Catch up on coverage from the second day of the 2026 American Academy of Dermatology Annual Meeting held in Denver, Colorado.
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AAD 2026 Late-Breaker: Lawrence Eichenfield, MD, on Phase 2 Success of Nemolizumab in Pediatric AD
Late-breaking phase 2 findings presented at AAD show nemolizumab achieved high EASI-90 rates and rapid itch relief in pediatric patients with atopic dermatitis.
Reactivating the Follicle: PP405 Moves Toward Late-Stage Trials for Alopecia
Pelage’s PP405 novel topical reawakens dormant follicle stem cells, showing signs of terminal regrowth and fueling late-stage alopecia research.
Late-Breaking Data: Roflumilast Cream 0.05% Demonstrates Efficacy and Favorable Tolerability in Infantile Atopic Dermatitis
At AAD 2026, Christopher Bunick, MD, PhD, and Patrick Burnett, MD, PhD, discuss late-breaking data of roflumilast cream's improvements in infants with AD.
Alumis’ Envudeucitinib Meets Co-Primary Endpoints in ONWARD1 and ONWARD2 Phase 3 Trials
Late-breaking data shared at AAD 2026 supports oral TYK2 envudeucitinib's efficacy and safety in moderate-to-severe plaque psoriasis.
Biogen Announces Positive Phase 2 Results for Litifilimab in Cutaneous Lupus Erythematosus at AAD 2026
This portion of the AMETHYST trial is the second successful phase 2 study of litifilimab, an investigational monoclonal antibody for CLE.
Late-Breaking Data: Zasocitinib Achieves Rapid Skin Clearance in Plaque Psoriasis
Phase 3 data presented at AAD 2026 show once-daily oral therapy clears skin as early as week 4, offering a fast-acting option for patients.
Sonelokimab Demonstrates High HiSCR100 Rates and Durable Responses in Hidradenitis Suppurativa
Christopher Bunick, MD, PhD, and Kristian Reich, MD, PhD, discuss the long-term efficacy of sonelokimab, with more than 60% of patients achieving HiSCR75 and approximately 30% reaching HiSCR100.
AAD Meeting Snapshot: Late-Breaking Data in Atopic Dermatitis
Missed the late-breaking sessions? Review our quick guide of all the need-to-know data from AAD 2026.
Breaking Down Zasocitinib Data at AAD 2026
Melinda Gooderham, MSc, MD, FRCPC, reviewed late-breaking zasocitinib data for psoriasis, noting that 70% of patients reached sPGA 0/1.














