Stem cell factor, a growth factor critical for melanocyte survival, may play an important role in the development of benign and malignant skin hyperpigmentation disorders.
Oral tranexamic acid combined with low fluence 1064 nm Q-switched Nd: YAG laser is an effective and safe melasma treatment, with outcomes that are better than oral tranexamic acid alone, according to a recent study.
Chemical peels offer important advantages for treating melasma. Researchers offer insights from a review of recent advances in chemical peel treatments in melasma and acne.
Melasma responds well to oral and locally injected tranexamic acid treatments, but clinical results from topical tranexamic acid administration have been disappointing, researchers report. They examined efficacy of a co-enhancer as a method to deliver the treatment.
Men present with melasma too, but there are differentiating factors compared with female melasma patients. Researchers offer insights from a literature review for effectively treating the male melasma patient.
A recent study examines the safety and efficacy of picosecond laser as a melasma treatment during a time when lasers are increasingly being used to treat the condition.
When should lasers be used to treat melasma? Mildred López Piñeiro, M.D. provides her insight in our new column on energy devices.
A growing body of evidence supports treating melasma with systemic or intradermal tranexamic acid. But melasma patients often relapse when they stop taking the antifibrinolytic agent, and research on tranexamic acid’s long-term efficacy and safety is limited.
A literature review on clinical evidence for melasma treatments suggests an evidence-based treatment ladder.
A small study examines platelet-rich plasma injection as alternative or adjuvant melasma treatment.