The Weekly Roundup: December 15-19

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Steroid-Sparing Solutions Gain Ground in Pediatric AD

Experts discuss innovative, steroid-sparing treatments for pediatric atopic dermatitis, emphasizing personalized care and proactive management strategies.

Vanda Files BLA for Imsidolimab in Generalized Pustular Psoriasis

The BLA is supported by phase 3 data demonstrating rapid skin clearance and sustained disease control in patients with GPP.

Considering Biologics and Shared Decision-Making in Moderate to Severe Plaque Psoriasis: Part 1

In part 1 of this Case-Based Roundtable supplement, experts discuss biologic treatment options for psoriasis, and balancing efficacy with patient needs.

Medicus Pharma Completes Phase 2 Enrollment of D-MNA Study to Non-Invasively Treat BCC

Topline results are expected in the first quarter of 2026.

First-in-Class Topical GT20029 Demonstrates Promising Phase 2 Efficacy and Tolerability for AGA

GT20029 shows promising results in treating androgenetic alopecia, enhancing hair density with minimal adverse effects in men after 12 weeks.

Clinical Evaluation of Bentonite and Alcea sulphurea Extract in the Management of Acne

A bentonite and Alcea sulphurea facial mask significantly improved acne severity and patient satisfaction in a recent clinical trial.

Balancing Pathophysiology and Patient Lifestyle in Acne Management: Part 1

In part 1 of this supplement, experts discuss current and emerging treatments for patients, considering lifestyle choices.

Safe Step Act Supports Timely Access to Essential Therapy

"In the states where there is no step therapy legislation, this is life-changing,” said Mark Lebwohl, MD, dean for clinical therapeutics at Mount Sinai and chairman emeritus of its Department of Dermatology, in a recent interview with Dermatology Times.

Considering Biologics and Shared Decision-Making in Moderate to Severe Plaque Psoriasis: Part 2

In part 2 of this Case-Based Roundtable supplement, experts discuss therapeutic options for psoriasis when considering involvement of special areas.

Wildfire Air Pollution Drives Surge in Clinic Visits for AD and Pruritus

Wildfire air pollution significantly increases atopic dermatitis and itch-related dermatologic visits, highlighting the urgent need for skin protection during poor air quality.

Reviewing the Overarching Umbrella of Psoriatic Disease

At the Horizons in Advanced Practice meeting, Douglas DiRuggiero, DMSc, MHS, PA-C, discussed psoriasis in high-impact sites, overall psoriatic disease, and available therapies.

Expert Panel Unanimously Backs DecisionDx-Melanoma for Guiding Personalized Cancer Care

An expert panel endorses Castle Biosciences’ 31-GEP test, enhancing melanoma management through personalized risk assessment and improved prognostic accuracy.

Journal Digest: December 17, 2025

This review of the latest dermatologic studies includes case studies on allergic contact dermatitis from UV nail polish, the introduction of the visual aesthetics methodology, and more.

Highlighting Major Breakthroughs for Atopic Dermatitis and Psoriasis in 2025

Discover the latest breakthroughs in atopic dermatitis and psoriasis treatments for 2025, enhancing patient care and individualizing therapy options.

DecisionDx-UM and PRAME Improve Metastatic Risk Prediction in Uveal Melanoma

New research reveals that combining DecisionDx-UM and PRAME significantly enhances survival predictions for uveal melanoma.

Phase 2a Results Demonstrate Safety and Efficacy of SGX302 Gel in Mild-to-Moderate Psoriasis

Soligenix reveals promising results from its phase 2a study of SGX302, a novel therapy for mild-to-moderate psoriasis, enhancing patient experience and efficacy.

FDA Clears IND Application of Recludix’s Oral STAT6, REX-8756

Early-phase development introduces a potential first-in-class oral approach targeting type 2 inflammation relevant to dermatologic diseases.

Building Better HS Treatment Plans Through Case-Based Discussions

Porter leads a dynamic roundtable on hidradenitis suppurativa, exploring innovative treatments and collaborative strategies for improved patient outcomes.

Balancing Pathophysiology and Patient Lifestyle in Acne Management: Part 2

In part 2 of this supplement, experts discuss therapies for inflammatory acne.

Topicals Demonstrate Targeted Control Across 3 Distinct Atopic Dermatitis Cases

At a recent Case-Based Roundtable event, Aaron Farberg, MD, moderated a discussion of challenging atopic dermatitis cases spanning adult, adolescent, and pediatric patients.

Phase 3 Data Position Zasocitinib as a Potential New Oral Option for Psoriasis

Zasocitinib emerges as a promising oral therapy for psoriasis, achieving significant skin clearance and favorable safety in recent phase 3 trials.

The Year Without a Dermatologist

Explore the risks of bypassing dermatologists for DIY skincare and telehealth treatments, highlighting real patient experiences and expert insights.

Stress Coping, Eosinophils, and Gender Differences in Adolescent Chronic Urticaria

A study reveals stress coping strategies and eosinophil levels impact CU in adolescents, highlighting the need for integrated psychological support.

Personalizing Psoriasis Care in Older Adults

Omar Noor, MD, recently presented 3 cases of psoriasis in older patients at Horizons in Advanced Practice to discuss available treatment options and considerations for Medicare and in-office patients.

Considering Biologics and Shared Decision-Making in Moderate to Severe Plaque Psoriasis: Part 3

In part 3 of this Case-Based Roundtable supplement, experts discuss psoriatic therapies for hair-bearing areas.

Dermatology Wrapped: 2025 Year in Review

What were the top dermatology hits of 2025?

Case-Based Insights Highlight Oral JAK Inhibitors for Alopecia Areata

Experts discuss real-world strategies for managing alopecia areata, emphasizing JAK inhibitors, psychosocial impacts, and personalized patient care approaches.

Practical Approaches to Managing Atopic Dermatitis With Topical Therapies

Douglas DiRuggiero, DMSc, MHS, PA-C, reviewed the 3 latest non-steroidal topicals for atopic dermatitis at the Horizons in Advanced Practice meeting.

The Aesthetic Edge: December 2025

Find out what skin care products and aesthetic innovations clinicians are recommending to patients for the month of December.

Sachin M. Shridharani, MD, FACS, Reflects on 2025 Trends and Predicts What’s Next in Aesthetic Dermatology

Discover the latest trends in aesthetic dermatology for 2025, including innovative treatments and the impact of social media on patient choices.

Dermatologic Effects of Energy and High Protein Drinks

Given the popularity of these products among young patients, it is important to consider their impact on common dermatologic conditions such as acne.

New Review Spotlights Keloid Treatment Gaps in Skin of Color

Discover effective treatment strategies for keloids and hypertrophic scars in skin of color, emphasizing personalized approaches and combination therapies.