Efficacy and Tolerance of a Polymeric Surfactant Technology–Based Cleanser

A recent study explored the efficacy and tolerance of a cleanser formulated with polymeric surfactant technology, specifically hydrophobically modified polymers (HMPs), in patients with clinically diagnosed sensitive skin. The study involved 85 participants suffering from conditions such as eczema, atopic dermatitis, rosacea, cosmetic intolerance syndrome, or acne. Over 4 weeks, participants used the foaming cleanser twice daily, and the study assessed both tolerability and efficacy. Remarkably, improvements were seen in skin attributes like visual smoothness, tactile softness, clarity, radiance, and overall appearance, all statistically significant. This demonstrates that simply changing to a suitable cleanser can notably enhance skin condition in sensitive individuals.

One of the most compelling findings was the improvement in patient sensory experiences, including reductions in tightness, itching, burning, and stinging. These symptoms often arise from a compromised skin barrier, and the HMP-based cleanser’s ability to support and repair this barrier likely accounts for the positive sensory changes. Some cleansers even contained moisturizing agents, contributing further to barrier repair and hydration without the immediate need for additional moisturizers. Objective measurements confirmed the product’s gentleness; there were no increases in erythema, irritation, peeling, dryness, or transepidermal water loss, and skin pH and hydration levels remained stable. Additionally, the microbiome was unaffected, indicating these cleansers are microbiome-friendly and do not disrupt the natural skin flora.

This comprehensive approach, combining clinical observations, self-reported symptoms, and mechanistic skin assessments, highlights the value of HMP technology in sensitive skin care. The study’s diverse participant group enhances its applicability across different demographics. Such findings underscore the clinical relevance of these polymeric cleansers, which provide effective cleansing with mild, skin-friendly surfactants that produce desirable foam without damaging the barrier. This makes them an excellent choice for a wide range of patients with sensitive skin, including those with underlying skin conditions or those experiencing self-perceived sensitivity.