Psoriasis

A Danish study suggests that TNF inhibitors may not increase the risk of developing recurring or new primary cancers in patients with inflammatory diseases.

Ustekinumab’s short-term effect on aortic vascular inflammation points to possible role of IL-12, IL-23 in cardiovascular disease, but more research is needed.

Pediatric patients with psoriasis who experience a significant improvement in disease severity after treatment may experience the greatest positive impact to quality of life, according to a recent study. 

Risankizumab (SKYRIZI, AbbVie), outperformed secukinumab (Cosentyx, Novartis) in a head-to-head phase 3 study comparing the two treatments in adult patients with moderate to severe plaque psoriasis, according to data released by the company Jan. 14.

Topical halobetasol propionate 0.01% lotion appears to safely and quickly improve lower-extremity psoriatic lesions, according to a recent study.

Results from an EU phase 3 clinical trial of a combination of betamethasone dipropionate and calcipotriene cream showed improved patient convenience, quality of life and efficacy compared to a betamethasone dipropionate and calcipotriene gel for patients with plaque psoriasis.

Newly published results from a phase 3 study demonstrate the superiority of bimekizumab over adalimumab for plaque psoriasis.

A recent study shows promising results for using ultrasound to examine hand tendon and joint inflammation in psoriatic arthritis patients.

Researchers recently undertook an epidemiologic study to investigate the prevalence of palmoplantar pustulosis (PPP) and co-existing plaque psoriasis. Read what they discovered in this article.

Pediatric psoriasis patients may experience comorbidities, including psychiatric comorbidities, at a greater rate than children without the disease, according to a recent study.

Researchers performed a systematic review of available reports on the therapeutic benefit of interleukin (IL)-17/T-helper 17 (Th17) axis inhibitors in patients with generalized pustular psoriasis (GPP). Read what they discovered in this article.

A recent, extreme case of psoriasis demonstrates how socioeconomic factors can lead to inadequate disease control. The solution? A personalized treatment plan, says the study authors.

Psoriasis often has a greater impact on quality of life in patients with skin of color as the condition and its treatment can result in long-lasting pigmentary changes. 

The 2019 joint American Academy of Dermatology and National Psoriasis Foundation phototherapy treatment of psoriasis guidelines comprehensively updates dermatologists and other providers on the state-of-the art use of various light modalities to treat psoriasis patients.

Oral health, habits and diet may influence disease severity in psoriasis, says a study published in the Dermatology Online Journal.

A study recently explored the differences in baseline characteristics between responders to anti-tumor necrosis factor (anti-TNF) therapy and insufficient responders with moderate-to-severe psoriasis. Read what researchers discovered in this article.

Interleukin-29 (IL-29) is a newly discovered cytokine that has become the subject of increased research attention for its role in inflammation and inflammatory autoimmune disorders and therefore as a target for novel therapeutic development.

With 4 decades of dermatology advances, we asked the very dermatologist experts who we often contact to help us to report on the milestones to weigh in on what they think have made the most difference in theirs and their patients’ lives.

Over the past 40 years, there have been major dermatological breakthroughs that have changed the way doctors treat patients, along with the very treatments they use. 

It is well established that psoriasis is associated with cardiometabolic disease, though the reason why remains unclear. This study followed pregnant women and mothers with psoriasis over an 11 year period to gain insight into the link between the immune-mediated skin disease and cardiometabolic disease.

Pruritus frequently afflicts psoriasis patients, but few studies explore the role of pruritus in regards to disease activity, pharmacotherapy or demographics. This study attempts to fill that gap.

Weight-based dosing of apremilast appeared to ensure comparable efficacy, safety and tolerability with in kids as in adults, and should be explored in future studies.

Psoriasis and atopic dermatitis patients want more nonsteroidal topical options. This expert breaks down newly available treatments and those to come.

Psoriasis has been strongly linked to metabolic and Type 2 diabetes, but the exact relationship between psoriasis and Type 2 diabetes remains ambiguous. This study aimed to fill that gap.

This slideshow breaks down important considerations to keep in mind when evaluating psoriasis patient for psoriatic arthritis.

A recent study discovered that body mass index (BMI) and age of disease onset may play a part in the development of hypertension in psoriatic arthritis and psoriasis. Read what researchers found in this article.

The realization of the critical importance of the IL-17 and 23 pathways have led to the development of numerous therapies that target parts of the immune system.

Researchers in Taiwan investigated whether behavioral modifications such as weight reduction, alcohol abstinence, smoking cessation and exercise could impact psoriasis severity. Read what they discovered in this article.

Researchers employed the the Citizen Pscientist, an online patient portal developed by the National Psoriasis Foundation, to investigate chronic sleep dysfunction prevalence in psoriasis. Read what they discovered in this article. 

In this table, we highlight how psoriasis treatments have evolved over the past four decades.