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Pediatric Dermatology

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In a continuing series from Dermatology Times , a panel of pediatric masters discusses treatment options for specific and unusual cases. This second case is that of a 13-year-old girl who presents a progressive area of alopecia over the frontal parietal scalp. There is an ivory scleratic plaque with an extension to the forehead. What do you do?

Source: www.biotechnologyhealthcare.com Austin, Texas ? Introgen Therapies announced initiation of a Phase II clinical trial of INGN 241 in patients with metastatic melanoma.

Source: www.PRNewswire.com Connetics Corp., a specialty pharmaceutical company focused on dermatology announced Thursday, April 8 that it has received confirmation that the FDA has accepted for filing the company's NDA for Extina, as of Jan. 26, 2004, with a user fee goal date of Sept. 24, 2004.

Liability reform

American Medical Association President Donald J. Palmisano, M.D., J.D., issued the following statement supporting S. 2061.

Oregon Health & Science University School of Medicine researchers hope treating babies newly diagnosed with eczema using the study drug Elidel will not only control painful skin flare-ups, but also ultimately prevent the onset of childhood asthma.

Physicians may not need to prescribe antibiotics when treating a common skin infection in children, according to researchers at UT Southwestern Medical Center in Dallas.

Connetics Corp. has agreed to acquire exclusive U.S. rights to Roche Holding AG's Soriatane (acitretin).

Acne drug problems

U.S. officials are considering again whether to tighten restrictions on the use of a prescription drug that is highly effective against severe acne but can cause birth defects.

Waikoloa, Hawaii - If eczema can be kept under better control during infancy and early childhood, it might be possible to reduce the atopic march and lessen the development of asthma and allergies in some children, said Adelaide A. Hebert, M.D. Topical immune modulators could play a role in keeping the skin barrier more intact and reducing a child's propensity to develop a high level of atopic diseases, added Dr. Hebert, professor and vice chairman, department of dermatology, University of Texas Health Science Center, Houston.

San Diego -- A new web-based teaching module addresses the 80-hour-work-week regulations to improve the dermatology knowledge base of pediatric residents. It could have broader applications, said Eliot Mostow, M.D., MPH.

Pediatric purpura

Miami, Fla. - Pediatric dermatologists and pediatricians often see children with purpura, which presents cutaneously but can be a sign of systemic abnormalities.

Techniques for tots

Washington, D.C. - Elective dermatologic surgeries in children have been enhanced by new technologies, new clinical research, new anesthesia, and new therapies. A five-member panel discussion held at the annual meeting of the American Academy of Dermatology highlighted many of these advances and provided practical tips for treating children over the age of 7.

Washington -- New therapies continue to emerge in pediatric dermatology, and recent studies demonstrate the effectiveness of such therapies. Ilona J. Frieden, M.D., highlighted studies in some areas of common concern in a presentation at the annual meeting of the American Academy of Dermatology.

Dosing strategies

Washington - The optimum doses of biologic treatments for psoriasis may be higher than previously believed, according to Mark Lebwohl, M.D., professor and chairman, department of dermatology, Mt. Sinai School of Medicine.

About 15 years ago, while riding on a shuttle bus at the annual American Academy of Dermatology meeting, I overheard two elderly dermatologists discussing the state of dermatology, as they perceived it. One gentleman commented that he had not seen a single advance to rival the advent of tetracycline for acne, and that most of the new treatments did not work very well. At the time, I remember thinking that these practitioners were out of touch with all of the hot new therapies for skin disorders. Since that time, as I have been bombarded by myriad new and supposedly revolutionary "advances," I, too, am beginning to question whether we should equate the concept of "newness"

Masters of pediatrics

Welcome to a new department in Dermatology Times. Beginning with this month's Special Report, DT will present a monthly panel review of specific cases in pediatric dermatology, an effort coordinated by editorial adviser Lawrence Schachner, M.D. In this installment, a panel of pediatric masters discusses treatment options for the unusual case of a 12-year-old Hispanic girl who was brought in by her parents for treatment of a white spot that had developed after she was out playing in the sun.

Washington - Cutaneous lesions are common in infants with neonatal lupus erythematosus (NLE) and may have life-long sequelae. However, the most worrisome associations are its noncutaneous features and the increased risks for a mother to develop an autoimmune disorder herself, said Amy S. Paller, M.D., at the annual meeting of the American Academy of Dermatology.

Boca Raton, Fla. - Contact dermatitis from topical medications is the most common type of adverse drug reaction, and allergic contact dermatitis is the most common and most important form of contact dermatitis induced by topical drugs, according to James S. Taylor, M.D., head of the industrial dermatology section of the department of dermatology at the Cleveland Clinic Foundation in Cleveland. "Patients with medicament contact dermatitis usually have a good prognosis, but with a propensity for relapse," Dr. Taylor said.

Maui, Hawaii - For thousands of years, people have flocked to the Dead Sea searching for relief for their itchy skin. Now, Chicago-area psoriasis and atopic dermatitis sufferers are bathing in reconstituted Dead Sea water at a suburban clinic.

Tampa, Fla. -- Dermatologists can use hypnosis as an adjunctive or monotherapy for helping patients relax for in-office procedures, feel less pain, or even change habits such as skin picking. What dermatologists might not know about medical hypnosis is it usually takes only one to three minutes to induce hypnosis, using a brief hypnotic technique, according to Philip D. Shenefelt, M.D., associate professor of medicine, Division of Dermatology in the Department of Internal Medicine, University of South Florida, Tampa.

PARTICIPANTSMarcia Glynn, MD Assistant Professor, Dermatology Director, PediatricDermatology Martin Luther King/Charles R. Drew Medical Center Los Angeles,CaliforniaJudy Hunter, MD Pediatrician Principal Investigator HealthCare PartnersMedical Group Torrance, California