Nutrafol Expands Portfolio with First and Only Hair Loss Supplement for Male Patients 50 and Older

Nutrafol has introduced Men 50+, a new nutraceutical positioned as the first hair growth supplement specifically formulated for men aged 50 years and older.¹ The launch expands the company’s life-stage–focused portfolio and reflects a growing emphasis on age-related biologic drivers of hair thinning in male patients, a demographic often managed with more generalized approaches.

Understanding Age-Related Hair Biology

“At Nutrafol, our mission has always been to support people through every phase of life,” Cindy Gustafson, CEO of Nutrafol, said in the press release. “We’ve long understood that hair health evolves with life stage. As men enter their 50s and beyond, their biology shifts in meaningful ways — yet options in the market rarely shift with them. Nutrafol Men 50+ was created to close that gap, addressing the age-related drivers of thinning and extending the same life-stage, whole-body approach that has transformed women’s hair health to men.”¹

Men 50+ was developed in recognition that hair biology evolves with aging and physiologic shifts may alter follicular cycling, hair fiber quality, and scalp health. This patient population experiences an approximate 20% decline in testosterone, reduced collagen production, increased oxidative stress, accelerated cellular aging, and diminished nutrient absorption efficiency.2 Ongoing stress and hormonal influences are also described as persistent contributors to thinning. Together, these factors are framed as necessitating a more targeted, “whole-body” strategy rather than a one-size-fits-all formulation.

The Science Behind the Formulation

The new product is a physician-formulated, vegan, drug-free oral supplement built around Nutrafol’s proprietary Synergen Complex Renewal. The formulation includes multiple ingredients selected to address purported root causes of age-related hair thinning:

• Saw palmetto is incorporated to help reduce conversion of testosterone to dihydrotestosterone (DHT), a pathway commonly implicated in androgenetic alopecia.
• Moldavian dragonhead is included to support natural collagen production, reflecting the role of dermal matrix integrity in hair anchoring and scalp structure.
• Spermidine, a polyamine associated with cellular renewal processes, is positioned as supporting improvements in hair thinning.
• A blend of probiotics, antioxidants, vitamins, and minerals are aimed at addressing common nutrient gaps in men over 50 and supporting scalp and follicular health in the context of increased oxidative stress and altered absorption.

Clinical Efficacy and Patient Outcomes

Nutrafol emphasizes that the supplement is designed to improve hair thickness, strength, and scalp coverage over time without negatively affecting sexual performance—an issue sometimes raised by patients regarding pharmacologic DHT-modulating therapies. The product is marketed for long-term support of existing hair and promotion of visibly fuller, healthier-looking growth. In a clinical study, 84% of participants reportedly experienced thicker, fuller hair, and 90% reported slowed hair thinning after 9 months.

“Hair thinning isn’t one size fits all, and men over 50 experience a distinct shift in hair biology that requires a different approach,” said Heather Woolery-Lloyd, MD, FAAD, Chief Medical Advisor at Nutrafol, in a statement. “Collagen declines, cellular aging accelerates, nutrient absorption decreases, oxidative stress increases, and hormonal balance evolves — all of which directly impact hair growth and quality. Nutrafol Men 50+ is specifically formulated to multi-target these age-related root causes from within. By supporting the body’s changing biology, we can help men maintain the hair they have while promoting visibly fuller, healthier-looking growth.”¹

Nutrafol Men 50+ is available directly to patients online and through e-commerce platforms, as well as via health care providers.

References

1. Nutrafol Introduced Men 50+, The First and Only Hair Growth Product Specifically Formulated for Men 50+. News release. Yahoo Finance. Published February 3, 2026. Accessed February 3, 2026. https://finance.yahoo.com/news/nutrafol-introduces-men-50-first-135700836.html?guccounter=1&guce_referrer=aHR0cHM6Ly93d3cuZ29vZ2xlLmNvbS8&guce_referrer_sig=AQAAALzYAvR9GSc-napfsOVodYI6n8LspyzQBjtoPL43c08VuNwq41ujIyrLoL9N9UIbG-Q1n2bYjMqH5ZxPuMsEJ_wTsx4tzWgLBWi14ezl2HxAwH4GqSkt6V5iEKOkm8MBdoozpVR4tGcKI3QEjeQs9FcogXzIMpcM8sBrvEYNGfjO

2. Cheng H, Zhang X, Li Y, et al. Age-related testosterone decline: mechanisms and intervention strategies. Reprod Biol Endocrinol. 2024;22(1):144. Published 2024 Nov 14. doi:10.1186/s12958-024-01316-5