Pediatric Dermatology

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ECZEMA TREATMENT

The mother of a four-year-old with eczema discovered Eucerin Dry Skin treatment after trying a number of treatments in an attempt to clear up her daughter's cracked skin.

New data suggest InterMune Inc.'s intravenous oritavancin is as effective as a regimen of vancomycin plus cephalexin in treating patients with complicated skin and skin-structure infections (CSSSI).

KINDLER'S SKIN DISORDER

Researchers in Austria set out to evaluate the recently proposed and debated characteristic immunohistochemical and ultrastructural features of Kindler's syndrome.

ROSACEA BOOKLET AVAILABLE

The National Rosacea Society has introduced the first consumer education booklet, "Understanding Rosacea," which incorporates the new standard diagnostic criteria for this common facial disorder.

VACCINE LAUNCH EXPECTED

CancerVax expects to launch its therapeutic melanoma vaccine and lead product candidate Canvaxin by 2006.

MATTER SETTLED

Cool Laser Optics (CLO) Inc., owner of patents regarding skin cooling, has reached an agreement with Lumenis Inc., a laser manufacturer, over issues regarding alleged infringement of certain CLO patents.

CONTROVERSIAL MEASURE

Before leaving office, California Governor Gray Davis signed new laws to boost controversial stem cell research seen as key to new medical advances.

LONG-TERM PUVA EFFECTS

Korean research suggests long-term photochemotherapy using psoralen and ultra-violet A irradiation (PUVA) may cause several adverse effects, including skin cancer, especially squamous cell carcinoma.

MELANIN CONTENT MEASURED

Researchers in Japan are quantifying different types of melanin in depigmented and repigmented patches of vitiligo following psoralen plus ultraviolet A (PUVA) therapy.

INVESTIGATING MELANIN

To examine whether glutathione is a major antioxidant in melanocytes, researchers at the Norwegian Radium Hospital, Oslo, Norway, depleted melanocytes of glutathione via buthionine sulfoximine.

Bacterial Superantigens

San Francisco - The presence of bacteria can have an effect on the course and severity of inflammatory skin diseases such as psoriasis and atopic dermatitis, according to Jeffrey B. Travers, M.D., Ph.D. An understanding of the mechanisms behind this effect will assist in choosing which patients may potentially benefit from antibiotic treatment as part of their therapy.

Chicago - Although some drugs used to treat psoriasis are known teratogens, dermatologists still have a range of options they might choose from for managing psoriasis across its spectrum of severity in women who are or wish to become pregnant, Mark Lebwohl, M.D., said at Academy '03.

Auckland, New Zealand - Intradermal injection of a purified cell wall component from heat-killed Mycobacterium vaccae may one day be used to treat children with severe atopic dermatitis, if a clinical program carried out by a New Zealand company continues to be successful.

The Skin Man

Being a drummer is nothing like being a dermatologist, but Arthur W. Richardson, M.D., does both with passion. Friends of the semi-retired San Antonio dermatologist would call him "the skin man" for his drum playing ability - that was before Dr. Richardson became a "skin doctor."

Topical Tx for Thin Skin

New York - With the results of two previous open trials supporting clinical use of tacrolimus (Protopic) and pimecrolimus (Elidel), current data affirms that the topical immunomodulators are the definitive treatment of choice for facial and intertriginous psoriasis, according to Mark Lebwohl, M.D.

Localized Psoriasis

Chicago - Innovative therapeutic approaches may be needed to manage patients with localized psoriasis who despite having only limited areas of disease can present a major therapeutic challenge for dermatologists, said Steven R. Feldman, M.D., Ph.D.

Astralis has begun Phase I clinical trial for Psoraxine for the treatment of moderate plaque psoriasis.

An advisory board to the Food and Drug Administration was unanimous in recommending the approval of Raptiva, a psoriasis drug manufactured by Genentech.

FDA APPROVES CUBICIN

The FDA has approved Cubicin, a product of Cubist Pharmaceuticals that was formally called Cidecin, for treatment of complicated skin and structure infections caused by gram-positive bacteria.

Atopic eczema is best treated before it actually flares up, according to research presented at the World Allergy Congress.

ACNE GEL TESTS WELL

A preliminary study shows that a peptide developed by Helix BioMedix Inc. can help reduce the severity of mild to moderate acne.