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Opinion|Videos|March 2, 2026

Tracking Progress After a Therapy Switch

Healthcare professionals discuss evaluating disease control and treatment response using objective findings and patient assessments in dermatology.

After switching therapy for a patient with psoriasis and psoriatic arthritis (PsA), evaluation requires a multi-faceted approach. For joint symptoms, the panel uses targeted physical exams, like palpating the Achilles tendon or lateral epicondyles, and ask specific questions about morning stiffness and pain after prolonged sitting. Objective improvement in nail pitting over 6-12 months can also indicate reduced systemic inflammation.

For skin disease, clinicians rely on a combination of tracked metrics and patient feedback. Objective measures include Body Surface Area (BSA) and Physician Global Assessment (PGA) to document plaque extent and thickness at each visit. Patient-reported outcomes, particularly the Dermatology Life Quality Index (DLQI), are essential to understand the treatment's impact on daily life and psychosocial burden. This combined method ensures both clinical targets and personal patient experience guide the assessment of treatment success.