The Aesthetic Edge: 2025 Product Recap
Key Takeaways
- Precision treatments with biologically active ingredients focused on skin communication, cellular repair, and inflammation modulation, using peptides, copper complexes, and antioxidants.
- Moisturizers evolved to support barrier restoration, collagen, and long-term skin health, incorporating growth factors, DNA repair enzymes, and ceramide-rich formulations.
Find out what skin care products and aesthetic innovations clinicians have recommended to patients in 2025.
This year, Dermatology Times introduced “The Aesthetic Edge,” a monthly roundup of the latest aesthetic formulas and innovative technologies dermatologists have been researching and recommending in the clinics. Read below to catch up on all the products we spotlighted in 2025!
Is there a new skin care product, technology, or trend that you think our dermatology community should know about? Email DT's Assistant Editor, Marie Bosslett (
Advanced Serums & Targeted Treatments
These high-performance formulas were designed to correct, repair, and rejuvenate skin, reflecting a continued shift toward precision treatment and biologically active ingredients. Peptides, copper complexes, antioxidants, and regenerative signaling molecules dominated this space, underscoring growing interest in skin communication, cellular repair, and inflammation modulation. Many of these formulations emphasize barrier compatibility and layered use, allowing clinicians to address concerns such as dyschromia, texture, and visible aging without increasing irritation or sensitivity.
Even Intensive Skin Tone Correcting Serum | skinbetter science Fortifying Peptide Shield | KARYNG by Dr. Karyn Grossman G Antioxidant Serum | Auro Skincare GHK-Cu Skin Cell Restorative Serum | Vitali Skincare Mystro Revive Renewing Serum | skinbetter science Needle Lift Peel Serum | YA-MAN Medi Lift Peptide Facial Refining Concentrate | ZO Skin Health Regenerative Complex | MUMUK Supreme Essence of Torricelumn | Elizabeth Grant Skin Care The Catalyst | Dr. Rossi DERM MD
Moisturizers, Creams, & Barrier Support
Barrier restoration remained a central theme, with moisturizers evolving beyond simple hydration to serve as active treatment vehicles. From daily hydrators to intensive overnight treatments, these products focus on strengthening the skin barrier, supporting collagen, and locking in moisture for long-term skin health and resilience. Collagen-supporting technologies, growth factors, DNA repair enzymes, and ceramide-rich formulations were frequently highlighted, particularly for post-procedure recovery and chronic inflammation. Additionally, nighttime formulations incorporating retinoids or reparative complexes reinforced optimized repair.
Barrier Shield Moisturizer | SHERAK Collagen Bank Face Moisturizers | Neutrogena Collagen ReActivate PM Lifting Treatment Moisturizer + Retinol | HydroPeptide DNA Defense Daily Cream | CielementsMD Growth Factor Repair Cream | Vitality Institute Nourishing Silk | FACTORFIVE Skincare The Great & The Hydro Layer | Caldera + Lab
Skin Prep & Sun Protection
Cleansers in this year’s roundup emphasized skin prep without barrier disruption, moving away from aggressive surfactants in favor of collagen-supportive systems. Gentle yet effective, these skin-prep formulas cleanse without compromising hydration, helping set the stage for active treatments while maintaining skin balance. Photoprotection continued to evolve with innovative SPF and UV-defense formulations that go beyond basic sun protection. Incorporating tone-correcting, antioxidant, and pigment-balancing benefits was a key trend.
HA⁵ Hydra Collagen Hydrating Foaming Cleanser | SkinMedica Sunlight Drops with Drop Finder Technology | Pour Moi Skincare ZnO+ Mineral Care CORRECT + FADE SPF50 | SunSolve MD
Acne Treatments & Body Care Innovations
Targeted solutions designed to address breakouts, post-acne marks, and uneven texture gained momentum this year with formulas that support healing while minimizing irritation. Clinical-grade ingredients and advanced technologies were formulated to improve overall skin health on both the face and body. The popularity of non-irritating spot treatments and occlusive healing technologies like these highlights a continued move away from overly aggressive acne management.
Acne Scar + Spot Corrector | Silagen AlphaRet Body Overnight Cream | skinbetter science Calm & Renew Lotion | Amlacatin The Pimple Patches | JB SKRUB
Hair, Scalp, & Follicle Health
Hair and scalp treatments in 2025 reinforced the growing understanding of the scalp as an extension of facial skin biology. Products featuring stem cell-derived ingredients, growth signals, and follicular support systems addressed hair thinning, density concerns, and overall scalp health. Many of these adjunctive, non-systemic therapies complement in-office hair restoration procedures, particularly in patients with alopecia and other forms of hair loss.
BLH308 System | Bomme Follicle Regenerative Spray | KERACELL MD MF Stemcell Scalp Essence & Cleanser | T Stem Care TopicalRx Beard Formula | Happy Head
Devices & Professional Technologies
Professional in-office as well as advanced at-home technologies have elevated skin care results through energy-based treatments, multi-step facials, and innovative delivery systems. This year, there was an emphasis on personalized, multimodal approaches that combine exfoliation, infusion, oxygenation, and light or laser-based therapies while also integrating with patients’ existing topical regimens.
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