Revolutionizing Acne Treatments and Skin Care with Cold Plasma Technology

Continuing an exclusive interview with Dermatology Times, Julia Zimmermann, PD, PHD, a biophysicist, medical researcher, CEO of terraplasma, and Managing Director of hyped about science shared the journey behind the groundbreaking cold plasma skin care device, PHLAS. Originally developed through scientific research at the Max-Planck-Institute for Extraterrestrial Physics and advanced through clinical collaborations, the PHLAS device represents a fusion of cutting-edge technology with dermatological care.

The cold atmospheric plasma technology, particularly using surface micro-discharge (SMD), has been rigorously studied since 2009. Research from the University Clinic of Regensburg and Dermatest demonstrated strong efficacy in inactivating acne-causing bacteria like Cutibacterium acnes. Clinical trials across Europe have supported PHLAS’s benefits for acne-prone skin, including reduced redness, refined pores, and fewer blemishes—all with a strong safety profile.

Developing PHLAS for at-home use, however, presented substantial challenges. Early prototypes were bulky and used complex systems like argon gas and microwave technology. To create a compact, consumer-friendly version, the team miniaturized components and engineered a safe, high-voltage system internally, necessitating custom electronics. But Zimmermann emphasized the biggest hurdle was public unfamiliarity.

“The biggest challenge is that nobody knows cold plasma,” she noted. “Nobody knows what it is, and we have to go out and explain what a cold plasma is to everybody. Nobody knows the benefits.”

PHLAS is unique among skincare devices, according to Zimmermann. Unlike most creams or liquids, plasma, a partially ionized gas, can penetrate pores deeply without additives. It mimics immune system responses, offering a natural, non-invasive treatment alternative. Zimmermann positions it as a professional-grade technology adapted for personal use. For dermatologists and clinicians, Zimmermann recommends PHLAS for patients struggling with acne, redness, and skin inflammation. The device is hygienic with exchangeable tips and designed for daily use after normal cleansing.

Looking ahead, terraplasma and hyped about science are launching PHLAS to the US market via Kickstarter on May 27. Future innovations may include plasma-compatible creams to enhance treatment absorption, which aligns with Zimmermann’s broader vision of revolutionizing skincare through science.