Dermatology Times 2024 In Review: Acne

Retinoid-Based Regimen Led to Significant Improvements in Skin Clarity Among Patients with Darker, Blemish-Prone Skin

The pilot study explored the use of double-conjugated retinoid serum used in combination with exfoliating peel pads.

Low Incidence of Elevated Liver Enzymes Exhibited Among Patients Using Isotretinoin

Researchers found that high levels of AST and ALT in patients with acne taking oral isotretinoin was low in incidence.

Ensure Your Patients Don’t Drop the Ball

This article discusses insights from research studies and offers specialized guidance aimed at dermatologists in hopes of fostering patient adherence in acne management.

AAD Releases Updated Guidelines for the Management of Acne Vulgaris

The guidelines update the American Academy of Dermatology’s 2016 recommendations for acne management in adults, adolescents, and children aged 9 and older.

What to Recommend for OTC Acne-Prone Skin Care

There’s nothing worse than having OTC products fight back against the progress we make with our prescription therapies.

John Barbieri, MD, MBA, FAAD: Evidence-Based Recommendations and Good Practice Statements From the AAD Acne Guidelines

Barbieri spoke with Dermatology Times to discuss the new guidelines and the recommendations and good practice statements included.

Suicide Risk in Isotretinoin Users: New Data

Despite its black box warning, isotretinoin does not appear to increase the risk of suicide in acne patients, a finding investigators say is reassuring in their research.

Tween Skin Care Mishaps via Misinformation on Social Media

Tween skin care has become a rising trend across social media platforms such as TikTok, and dermatology clinicians are becoming increasingly concerned about misinformation.

Breaking Down Benzene Testing Methods of Benzoyl Peroxide Products

On March 6, 2024, Valisure, an independent testing laboratory, found high levels of benzene when BPO products were incubated at 37°C, 50°C, and 70°C.

Mastering the Challenges of Adult Female Acne in Primary Care in 2024

Over 50% of women in their 20s and over 35% of women aged 30 to 39 years struggle with adult female cystic acne.

Allergan Aesthetics Launches 2 Products For Acne-Prone Skin

Mona Gohara, MD, explained the importance of the products' impact on the skin barrier.

Benzene Found in Benzoyl Peroxide-Containing Acne Products: What Comes Next?

Take an in-depth look at the basis of Valisure's benzene testing methods and practical recommendations for clinicians from Christopher Bunick, MD, PhD.

Lindus Health and Acinonyx Bio to Partner in Clinical Trial Evaluating a Benzoyl Peroxide Alternative

Acinonyx Bio's topical cream, ACX, targets Propionibacterium acnes.

Acne-Specific Quality of Life Questionnaire Developed

Am acne-specific HRQoL questionnaire developed in Europe could help to create more comprehensive, individualized treatment plans.

Rehmannia Glutinosa Leaf Extract Led to a Decrease in Acne Severity and Improved Skin Hydration, Quality of Life

Supplementation with RGLE led to clinically significant improvements in patients with acne vulgaris, according to a study.

Hormonal and Mental Health Implications of Acne: Selecting Appropriate Treatments for Patients

Although acne is common for most people to experience in their lifetime, it is important to individualize treatment and provide appropriate care when working with a diverse patient base.

Concurrent Isotretinoin-Fractional Radiofrequency Treatment Outperforms Delayed FRF Therapy 6 Months After ITN Cessation

Patients with acne scarring who received concurrent therapy with isotretinoin and fractional radiofrequency achieved significant reductions in acne scar volume.

Study Investigates CBD as Acne and Acne Scar Treatment

Researchers found that the hemp derivative addressed multiple facets of acne pathophysiology and improved acne scarring overall.

Patients, Providers Seek Therapeutic Alternatives to Benzoyl Peroxide

Some patients may be looking for alternatives to BPO, questioning its safety.

General Practice Evaluation of the TARGET Acne Toolkit

A study found that pharmacy professionals had an increased level of capability, opportunity, and motivation after accessing the resource.

Physicians Should Prepare for Potential Acne Vulgaris Misinformation Correction, Report Says

Social media misinformation related to acne vulgaris may require clinician intervention when discussing treatment with patients.

Study Highlights Efficacy of Lotion with Biotechnological Phytocomplex, Niacinamide, and Succinic Acid in Enhancing Microbiota Diversity and Reducing Acne Severity

The lotion effectively rebalanced the microbiota, reduced erythema and desquamation, and improved acne severity.

Patients With Acne Vulgaris Exhibit Lower Levels of Serum Zinc, Selenium, and Vitamin D Than General Population

Patients with acne also had higher rates of abnormal zinc and vitamin D levels, especially in severe cases.

Microneedling and CO2 Lasers Enhance Acne Treatment

A study revealed that CO2 fractional laser was significantly more effective than microneedling for acne treatment with ALA-PDT.

Comparing Energy-Based Devices for Acne

Although EBDs provided improvements over controls, they did not match the sebum reduction levels achieved by isotretinoin or hormonal therapies.

GLP-1 Agonists Not Linked to the Development of Acne

Acne vulgaris has been reported as an adverse effect of GLP-1 receptor agonists by some patients.

Understanding and Treating Pseudo Acne Fulminans

Shanna Miranti, MMS, PA-C, reviews 2 patient cases of pseudo acne fulminans, offering perspectives on treatment and management strategies.

FDA Clears Accure’s Laser System for Long-Term Treatment of Acne

This new indication adds to existing clearance of a non-drug treatment for mild to severe inflammatory acne vulgaris.

Study Reveals Comparable Efficacy of Clascoterone, Trifarotene, and Tazarotene in Acne Treatment

The meta-analysis revealed comparable efficacy in treating acne vulgaris and was presented at Fall Clinical 2024.

Probiotics Effective for Moderate Acne When Used with Doxycycline

The clinical trial showed promising results for patients who used probiotics as an accompanying treatment.

CAB Gel Shows Promising Results for Hispanic Patients with Acne

The study demonstrated significant reductions in inflammatory and non-inflammatory lesions for Hispanic patients using CAB gel.

Clascoterone Cream 1% Deemed Stable When Combined With Other Topical Acne Treatments

A poster presented at the 2024 SDPA Fall Conference demonstrated that clascoterone cream remains stable when paired with commonly prescribed acne topicals, supporting its role in multimodal therapy.

Study Reveals 90% Acne Severity Reduction with TF-LDM

Research suggested acne is primarily inflammatory, occurring even in unaffected skin, redefining its pathophysiology.
Patients Treated for Acne Exhibit Higher Sebum, Hydration, and TEWL Levels than General Population

These findings further suggest the implications of acne vulgaris treatment on the skin barrier.

Efficacy of Combining Postbiotic Formulation with Microneedling for Acne

Researchers stated that therapy represents a “valuable nonpharmacological intervention that offers an innovative therapeutic alternative” for acne treatment.

Several Risk Factors, Including PAE, Associated with Acne Scarring in Thai Patients

Researchers noted higher correlations in those who are prone to severe acne and post acne erythema (PAE).

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