Combination therapy cost-effective for treating severe onychomycosis

Washington - In patients with severe toenail onychomycosis, combination topical and systemic antifungal therapy - consisting of locally applied amorolfine 5 percent nail lacquer plus oral terbinafine or itraconazole - improves response rates and is more cost-effective compared with oral treatment alone, according to research presented at the annual meeting of the American Academy of Dermatology.