Two recent experiences have prompted me to tilt at still another windmill - that of overuse of systemic antibiotics. The first occurred two weeks ago when my neighbor and friend asked me to evaluate him for a three-day history of a persistent headache. (Why is a dermatologist doing this?) A clinical examination revealed right supraorbital tenderness and a normal neurologic condition, including full function of the right eye muscles and pupils. A clinical diagnosis of right frontal sinusitis was made and he was started on azithromycin.