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New Orleans - The experience of a teenage girl treated successfully with infliximab (Remicade) for severe, recalcitrant psoriasis of her hands and feet indicates the value of the TNF-alpha chimeric monoclonal antibody as a therapeutic option for psoriasis.

New Orleans - Second intention healing with a calcium alginate dressing can be a useful alternative for closing skin-cancer excision facial defects in select patients who might otherwise be managed with primary closure, local flaps, or skin grafts, Roger H. Weenig, M.D., M.P.H., said at the annual meeting of the American Academy of Dermatology.

Rockville, Md. - A three-drug combination for the treatment of melasma is available as a single formula after being used separately since the 1970s.

New Orleans - Dermatologists should maintain awareness that cutaneous lesions on the face or neck may have a dental origin, Julie L. Cantatore, said at the annual meeting of the American Academy of Dermatology.

New Orleans - Data from an open-label study suggest that the anticonvulsant drug gabapentin (Neurontin) added to antiviral treatment during acute herpes zoster infection may further reduce the duration and severity of postherpetic neuralgia, Mathijs H. Brentjens, M.S., M.D., reported at the annual meeting of the American Academy of Dermatology.

Miami Beach, Fla. - Isotretinoin (Accutane) causes depressionand mood changes but all cases can be managed for successful results, RonaldC. Hansen, M.D., said here at the annual Masters of Pediatrics meeting.

New Orleans - Just like the endothelial cells that proliferateand produce hemangiomas, the field of study that surrounds these benigntumors of infancy and childhood continues to be a work in progress, MoiseL. Levy, M.D., said at the 60th annual meeting of the American Academy ofDermatology.

Miami Beach, Fla. - The acne war chests of dermatologists haveexpanded with new devices, including azelaic acid, retinoids, and oral antibiotics.The FDA has even added oral contraceptives to the armamentarium.

Miami Beach, Fla. - The acne war chests of dermatologists haveexpanded with new devices, including azelaic acid, retinoids, and oral antibiotics.The FDA has even added oral contraceptives to the armamentarium.

Miami Beach, Fla. - Dermatologists and pediatricians often areafraid of learning the technicalities of the human genome. However, onlya basic knowledge, an understanding of how genetics might apply to practice,and a relationship with a geneticist who can answer your questions are necessaryto use the tools available today, Judith G. Hall, O.C., M.D., said.

* Never use the same product year-round. "Because skin isa living organ that's constantly affected by everything from hormones tohumidity, I use a variety of products - some only in certain seasons andothers just on certain days," says Susan Taylor, M.D., director, Skinof Color Center at St. Luke's Roosevelt Hospital, New York.

Money Matters

Q: I'm planning on buying a vacation home that ultimately willbe where we will live during retirement. Should I pay cash for the homeor apply for a mortgage?

Chicago - Oritavancin (InterMune), an investigational glycopeptidewith activity against a wide range of Gram-positive pathogens, has beenshown to cut the treatment time in half for complicated skin and skin structureinfections (CSSIs) compared to current standard therapy with vancomycinplus cephalexin, Margaret Wasilewski, M.D., said at the 41st InterscienceConference on Antimicrobial Agents & Chemotherapy.

Lobbyists for insurance companies, the managed care industry, and dozensof large trade associations are worried. Their old buddy, PresidentBush, has been talking to one of their biggest enemies, Sen. Ted Kennedy(D-MA), about, heaven forbid, managed care reform.

A few tips on relaying medical dataWe all have the experience of reading medical literature hoping thatthe articles will give new insights into skin disease and its management. There is often that vague discomfort that the data and their interpretationare not necessarily objective. This may be true for many reasons, includingconflicts of interest by the authors, optimistic spins from true believers,or honest misinterpretations of complex information. There are severalways that readers can be guided through this morass by the authors. Ifthe following footnotes were added at the end of scientific reports, itwould be a major assist to the readers:

San Francisco - Blood samples taken throughout three decades suggestthat at least one out of every four gay men living in San Francisco hasKaposi's sarcoma and doesn't know it, according to a report by HealthScoutNews

Seattle - Already approved for the treatment of rheumatoid arthritis,the FDA granted approval that extends etanercept's (Enbrel) use to the treatmentof psoriatic arthritis for the one million American sufferers.

Chicago - A new acne drug under development shows promise of efficacyand does not produce resistance in bacteria that causes the condition. Thenews comes at a time when the bacterium P. acnes demonstrated resistanceto traditional treatment antibiotics tetracycline and erythromycin.

Dundee, Scotland - A disease that was once officially declaredfree from "the world and its peoples" by the World Health Assemblyin 1980, endemic smallpox may now be lurking in the shadows by way of bioterrorism.

Baltimore - Phase II study results point to the potential roleof HspE7 as a safe and effective immunotherapeutic agent for the treatmentof genital warts and other HPV-related sexually transmitted diseases, KeertiV. Shah, M.D., said.