Dermatology Times, November 2020 (Vol. 41, No. 11)

Risankizumab outperforms secukinumab at one year

October 27, 2020

A phase 3b study investigating the efficacy and safety of risankizumab compared to secukinumab showed positive results, with risankizumab demonstrating noninferiority to secukinumab at week 16, and superiority at week 52.

Strategies for choosing and using neuromodulators

November 20, 2020

All safe and effective, the four neuromodulators with cosmetic indications have nuanced differences worth considering. Seth Matarasso, M.D., explains the benefits of these cosmetic neuromodulators, and reveals how to know when to choose the right one.

Treatment improves QOL for patients with acne

November 12, 2020

Quality of life could play role in assessing acne patient care. According to recent study’s results, researchers saw a four-to-five-fold QOL improvement versus baseline over a full treatment course of isotretinoin.

FDA accepts NDA filing for topical papulopustular rosacea treatment

September 14, 2020

The U.S. Food and Drug Administration (FDA) has accepted the New Drug Application (NDA) filing for Sol-Gel’s Epsolay, a 5% microencapsulated benzoyl peroxide cream for the treatment of inflammatory lesions of rosacea or papulopustular rosacea.

Smartphone apps not effective in skin cancer risk

November 17, 2020

Researchers conducted a critical appraisal of a systematic review of six different smartphone apps and found little evidence that they are effective in self-monitoring or skin cancer detection, according to a recent study.

Robotic-controlled laser advances body contouring

November 18, 2020

A novel robotic-controlled 1064-nm laser brings efficiency and precision to body contouring. The clinical trial supporting FDA clearance of the device showed its effectiveness based on blinded photographic assessments, ultrasound measurements and circumferential assessments.

Mohs micrographic presents challenges in kids

November 25, 2020

While Mohs micrographic surgery is well established as a safe and effective therapeutic modality in adult patients, it is not as commonly used in pediatric populations. There are unique challenges to performing Mohs surgery on pediatric patients, especially with patient cooperation. Multidisciplinary planning may be needed.

HIPAA, COVID-19 and jail

November 13, 2020

David J. Goldberg, M.D., J.D., explains how a terminated employee can violate HIPAA if they access medical records of other associates at their former place of work, even if they find out one of those associates had COVID-19 and did not disclose it to the office.

Adjunctive examined for facial erythema

November 24, 2020

Investigators assessed results combining oxymetazoline and four different lasers in a recent phase 4 study. Results demonstrate improvement from baseline in Clinician Erythema Assessment (CEA) score.

Biologics, small molecule drugs expand AD options

November 03, 2020

Dupilumab and JAK inhibitors are leading the way in atopic dermatitis treatment, but there are numerous clinical trials of both new biologics and new small molecule drugs, and future treatment regimens likely will utilize both.

Caffeine's role in skincare

November 20, 2020

Caffeine holds certain properties that may benefit the skin. As an antioxidant, it may decrease the production of reactive oxygen species and free radicals as well as damage from ultraviolet radiation. It may even play a role in promoting hair growth.

Gene expression profile test predicts metastatic risk

November 18, 2020

Investigators of a recent study found a 40-gene expression profile (40-GEP) test helps improve identification of high risk for metastatic disease in patients with cutaneous squamous cell carcinoma (cSCC).

3D imaging technique measures severity of atrophic acne scars

October 11, 2020

There is a dire need to improve the clinical tools dermatologists use to assess the severity of acne scars. This 3D imaging technique may help, according to a recent study presented at the 2020 virtual American Society for Dermatologic Surgery (ASDS) meeting.

Novel device characterizes mite infestations

November 25, 2020

Fluorescence-advanced videodermatoscopy (FAV, Adamo Srl) for characterization of Demodex mites suggests that it can be a useful tool in the clinical evaluation and management of patients with Demodex-related skin diseases.

Skin of color patients lacking in psoriasis trials

November 03, 2020

A majority of psoriasis patients in phase 3 clinical trials for biologics are white, says authors of a recent study. As ethnicity and race may play a role in response to biologics, researchers emphasize need for more diversity in clinical trials.