Pediatric Dermatology

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A retrospective, longitudinal cohort study was undertaken to analyze the effects of the FDA advisory on off-label topical calcineurin inhibitor (TCI) treatment practice patterns for infants with atopic dermatitis (<2 years of age). The results show a reduction in overall utilization of AD-related medications and reduced utilization of TCIs coupled with early introduction of topical corticosteroid treatment after the advisory compared to the period preceding the advisory.

Vascular laser surgery for port wine stains has led the way in pediatric dermatology surgery and can significantly improve the condition. The period from six to 18 months offers a good window for treatment.

The standard treatment for uncomplicated infantile hemangiomas continues to be active nonintervention, but researchers are making headway in offering faster options than the watch-and-wait approach.

Techniques for tots

Achieving good cosmetic surgical outcomes in children can be challenging, as issues of compliance play a pivotal role in maximizing outcomes. According to one specialist, success hinges on following some tricks of the pediatric trade.

Studies to date have revealed interesting findings in the structure aInd function of healthy infant skin and how those features change during infancy. This research may lead to the development of better infant skincare products.

Studies to date have revealed interesting findings in the structure aInd function of healthy infant skin and how those features change during infancy. This research may lead to the development of better infant skincare products.

Washington - The Food and Drug Administration (FDA) has issued a new warning about omalizumab, an asthma drug marketed by Genentech as Xolair, and has requested that the manufacturer add “black box” warnings to the product’s label reflecting the risk of anaphylaxis.

Danville, Pa. - Effective office-based patch testing requires physicians to go beyond the limits of a popular commercially available test, when possible, and take second readings on every patient, an expert says.

Pittsburgh - New "activated" moisturizers help the skin retain moisture, and they also repair abnormalities with the skin at baseline in atopic dermatitis patients, according to Douglas W. Kress, M.D., of Children's Dermatology Services at Children's Hospital of Pittsburgh.

Coral Gables, Fla. - Stiefel Laboratories' recent purchase of Connetics blends Connetics' innovative vehicle technology with Stiefel's worldwide marketing reach, company officials say. For dermatologists and patients, the acquisition augurs a steady stream of new applications for vehicles including the popular, patient-friendly foam pioneered by Connetics.

International report - French surgeons have performed the world's third partial face transplant - with "already amazing" results - on a man suffering from the rare genetic disorder neurofibromatosis.

Hanover, N.H. - A community-wide sun safety intervention targeting middle-school-aged children was effective in changing sun-protection behaviors and reducing skin cancer risks, WebMD reports.

National report - The Food and Drug Administration's role is a necessary one, dermatologists say, but regulatory red tape can slow the introduction of new drugs into the marketplace, and post-marketing restrictions can hamper efforts to deliver effective medications to patients.

Omaha, Neb. - A patient presenting to a primary care physician with complaints of an arm rash may not be particularly unusual, but one unusual case illustrates the need for proactive cooperation between primary care physicians and specialists to best serve the patient's needs.

The severe hyperpigmentation began at 2 weeks of age and continued until 8 years of age, when the pigment began to disappear leaving behind a light-brown colored skin and numerous lentigines.