Why Patients Are Choosing Regenerative Aesthetics Over Quick Fixes

In the second part of her interview, Robin Smith, MD, MBA, a leader in regenerative medicine, discussed the growing demand for non-invasive aesthetic solutions that promote long-term skin health rather than temporary results. According to Smith, today’s patients are moving away from injectables and fillers that offer immediate but artificial effects. Instead, they are seeking functional, regenerative tools that improve skin over time, like Exoceuticals’ exosome-powered products with fast-acting and long-lasting benefits.

“I think over the years, people have really changed what they want. They don't want just a quick fill, right?” Smith said. “They really want things that will help the longevity of their skin, that will help make their skin healthier and look better for longer. And they're looking more for functional products.”

Clinical results support the efficacy of Exoceuticals’ products. For example, the brand’s EXO FACE Perfection Moisturizer demonstrated statistically significant reductions in crow’s feet within just one week, and improved skin luminosity, elasticity, and hydration by day 28. This is achieved through a combination of engineered exosomes and advanced ingredients that promote the production of collagen, elastin, and hyaluronic acid, restoring the skin’s natural barrier and firmness.

Smith also highlighted the broad relevance of regenerative aesthetics, particularly for individuals affected by environmental stressors, aging, hormone changes, or the effects of medications such as GLP-1 receptor agonists. She also points out the growing need for skin and hair support due to increased incidences of hair thinning linked to stress, illness, and nutrient deficiencies. Since hair follicles are part of the skin, these same regenerative ingredients can benefit both skin and hair health.

A common misconception Smith addressed is that “more is better” when it comes to exosomes. In reality, exosomes function like bioactive compounds with optimal dosages. Overloading skin with exosomes can lead to receptor saturation or unintended effects.

“Not enough isn't good, but too much may not be better. There’s a dose curve just like there is with any biologic,” Smith noted.

She emphasized that not all exosomes are the same; their source, manufacturing process, and bioactive cargo all influence their function. Exoceuticals’ exosomes are specifically engineered for effectiveness and paired with complementary ingredients such as multilevel hyaluronic acid and bio-convertible vitamin C.

Ultimately, Smith advocates for a science-driven, personalized approach to regenerative skincare. Exosome-based products can be tailored to a wide range of skin types and concerns, providing individualized support for healthier, more resilient skin from the inside out.