News|Articles|September 20, 2025

EADV 2025: Day 3 Recap

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Key Takeaways

  • OX40 and JAK inhibition offer complementary strategies for long-term atopic dermatitis control, as showcased at EADV 2025.
  • KT-621, an oral STAT6 degrader, showed biomarker reductions consistent with or superior to dupilumab in Phase 1 results.
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Catch up on coverage from the third day of the European Academy of Dermatology and Venereology Congress 2025 held in Paris, France.

The third day of the European Academy of Dermatology and Venereology Congress is complete! Check out our day 3 recap below. To stay informed with the latest insights live from Paris, France, subscribe to receive our eNewsletters and follow Dermatology Times on LinkedIn, Facebook, and X.

Guttman-Yassky Showcases 2 Paths to Long-Term AD Control at EADV 2025

At EADV 2025, she showcased how OX40 and JAK inhibition offer complementary approaches to long-term disease control.

KT-621 Shows Strong Phase 1 Results as First-in-Class Oral STAT6 Degrader

The oral degrader produced biomarker reductions consistent with or superior to dupilumab.

Rocatinlimab Maintains Safety Profile in 24-Week AD Study

Together with earlier trials presented at EADV, these findings support OX40 receptor inhibition as a promising therapeutic approach for AD.

DELTA TEEN Trial Demonstrates Superiority of Delgocitinib Cream in Adolescents With Chronic Hand Eczema

Late-breaking EADV 2025 presentations highlighted positive efficacy outcomes in the adolescent population and pooled safety data across 5 phase 2b and phase 3 trials of delgocitinib cream.

Bunick Discusses Dual-Target Biologic at EADV 2025

Galvokamig, a biologic targeting IL-13 and IL-17A/F, demonstrated significant benefits in moderate to severe atopic dermatitis.

APG777 Trial Demonstrates Efficacy, Safety in AD

Treatment with APG777 led to a significant 71.0% reduction in EASI scores from baseline to week 16, compared to a 33.8% reduction with placebo.

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