Oral Systemic Treatment Options for a 28-Year-Old Woman With Moderate Atopic Dermatitis

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• Please provide your initial impressions of this case. Does the involvement of the patient’s hands influence your management plan at all?
• How would you address the patient’s concerns regarding potential adverse effects of topical corticosteroids?
• Describe your approach to treatment options for this patient. What patient-specific factors would you take into consideration when deciding on a treatment?
• In what scenarios would a JAK inhibitor be preferred over another systemic agent?
• How would decide between a topical or systemic JAK inhibitor for a patient?
• What can the patient expect in terms of efficacy and safety with upadacitinib? When should she expect initial symptom relief?