Case Study 2: Managing Severe Infant Flares

In this case of an 18-month-old infant with a rapid, severe atopic dermatitis flare over 6 weeks, experts emphasize a careful diagnostic approach. Dr. Golant stresses investigating potential triggers or infection, given the acute change despite prior topical corticosteroid use. She highlights the profound quality of life impact, as sleep disruption affects the entire family unit. With 15% BSA involvement and unsatisfactory response to hydrocortisone and desonide, a deeper discussion on escalating therapy is needed. This includes considering more potent topical options (both steroidal and non-steroidal) and introducing the possibility of systemic treatments. The case underscores the need to rule out external factors while addressing moderate to severe disease with a comprehensive treatment plan for pediatric patients.