Opinion|Videos|January 10, 2025

Optimizing Severe Prurigo Nodularis Treatment in a 65-Year-Old Male With Multiple Comorbidities

A panelist discusses how this patient's history of chronic kidney disease, diabetes, and psychological stress are significant contributing factors to his prurigo nodularis, necessitating a comprehensive treatment approach that addresses both the underlying conditions and the itch-scratch cycle.

  • Please provide your initial impressions of this case. What factors in this patient’s history may be contributing to his prurigo nodularis?
  • What are the treatment goals for this patient? What nonpharmacologic measures would you discuss with this patient to aid in breaking the itch-scratch cycle?
  • Describe your approach to treatment options for this patient. Would he be a candidate for a systemic treatment such as dupilumab or nemolizumab?

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