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Treatment options for plaque psoriasis include topical medications, phototherapy, and systemic medications used individually, in combination, or sequentially. The goal of therapy is to optimize both patient response to treatment and patient quality of life. Because psoriasis is a chronic disorder that can have serious psychosocial consequences, an aggressive approach to plaque clearance, followed by maintenance therapy, is often warranted. This monograph provides an update on the topical treatment approaches that have proven successful in the short-term and long-term management of psoriasis, as well as a look at how topical treatments may fit with new biologic treatment strategies.

Topical treatments for psoriasis have been the mainstay of treatment strategy, but their use has evolved and will be impacted with the emergence of biologic therapies. This program has been designed to provide an overview of the latest available therapies to help physicians understand the important role topical treatment will continue to play in the new age of biologics. This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the US Food and Drug Administration (FDA). Health Management Solutions, Inc, the Dannemiller Memorial Educational Foundation, and Warner Chilcott do not recommend the use of any agent outside of the labeled indications.

Dermatologists and other physicians should be aware of several key recent developments at the Centers for Medicare & Medicaid Services (CMS) that could affect their practices.

Do over-the-counter medications and primary care treatment lower dermatologists' acne treatment load?

Dallas - What is the nurse's role in the administration of ALA-PDT (5-aminolevulinic acid[ALA]-photodynamic therapy [PDT])? At Gold Skin Care Center in Nashville, the better question might be: What is the physician's role in offering this therapy, which involves the use of a laser or light source plus an enhancer, ALA HCl topical solution, 20 percent, (Levulan, DUSA Pharmaceuticals)?

Washington - Dermatologists need to keep cosmeceuticals under the magnifying glass and identify the science supporting their efficacy so that they can better advise patients about over-the-counter skincare, said Patricia Farris, M.D., at the annual meeting of the American Academy of Dermatology.

Washington - The number of potential dermatologic uses for botulinum toxin type A (Botox Cosmetic) continues to increase, but the already sizable list probably only represents the tip of the iceberg, says Seth L. Matarasso, M.D., at the annual meeting of the American Academy of Dermatology

San Diego - The innate immune system may play a role in rosacea, according to Richard L. Gallo, M.D., Ph.D., from the Veterans Medical Research Foundation here and the University of California San Diego.

Dundee, Scotland - A routine cell culture of a patient with epidermolysis bullosa simplex (EBS) has led to the inadvertent discovery of a revertant mutation that deactivates the original pathogenic mutation, according to Irwin McLean, Ph.D.

Dr. Jane is a pillar of the dermatologic medical community. She has practiced in her small rural town for 10 years, is loved by her patients, and respected by her peers. She is active in community services, considers herself a religious person and has never been the recipient of any legal complaint.