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San Francisco - Etanercept (Enbrel) produces rapid, significant, and sustained improvement in symptoms in patients with moderate to severe psoriasis, according to the results of a large, multicenter Phase III study presented by Alice Gottlieb, MD, Ph.D.

Toenail Cure Rates

San Francisco - Thanks to their effectiveness against dermatophytes and their ability to concentrate in the nail plate, itraconazole (Sporanox) and terbinafine (Lamisil) have transformed toenail onychomycosis from a chronic condition to a curable disease.

San Francisco - Based on clinical efficacy data, botulinum toxin A (Botox) should become the treatment of choice for suppressing axillary hyperhidrosis, according to Nicholas J. Lowe, M.D.

San Francisco - Two large phase III studies involving 15 percent azelaic gel (Finacea) for the treatment of rosacea each resulted in more than a 50-percent reduction in the number of lesions.

San Francisco - Uncovering and successfully treating itch may depend on how readily dermatologists accept that some cases may be related to neurological or psychological factors, John Y.M. Koo, M.D., said at the annual meeting of the American Academy of Dermatology.

San Francisco - A book-in-progress will document the experiences of women dermatologists and articulate issues important to them, Gloria Graham, M.D., said at the annual meeting of the American Academy of Dermatology.

San Francisco - Daily antiviral therapy can prevent transmission of genital herpes simplex virus (HSV-2) from an infected individual to his or her partner, according to Stephen K. Tyring, M.D., Ph.D.

San Francisco - Octyl-2-cyanoacrylate products can play a useful role in woundcare as tissue adhesives, dressings, and antibacterial sealants, William H. Eaglstein, M.D., said at the annual meeting of the American Academy of Dermatology.

New Blood

Dermatology resident Steven Q. Wang was relaxing one Sunday last August, reading The New York Times. He never got past an article on the first page about how an AIDS tragedy sweeping through China's rural heartland was creating an "explosion of destitute orphans."

Although August is when the Internal Revenue Service traditionally begins selecting those 2002 tax returns that are to be examined in more depth, many dermatologists found themselves being targeted for examination soon after the April 15 tax deadline. After all, April 15, was also the deadline for participating in the IRS's "Offshore Voluntary Compliance Initiative" (OVCI), a "come back into the fold and you will be forgiven your tax transgressions" program.

Q. I recently attended a seminar on how to protect assets from potential lawsuits that detailed a number of complicated strategies, all of which seemed rather impractical and expensive. From a practical standpoint, which of the various asset-protection techniques are dermatologists successfully utilizing?

Today I gave a four-hour series of talks at the Vancouver Airport Fairmont Hotel for Altus Medical, a laser company.

Clean Sweep

San Francisco - Laboratory studies show that Olay Daily Facial cloths do not damage the stratum corneum, according to investigators for Procter & Gamble, maker of the products.

Blood Thinners

San Francisco - Medically necessary blood thinners should be continued in patients undergoing cutaneous surgery, said Clark C. Otley, M.D.

Tainted Donors

Modena, Italy - Kaposi's sarcoma (KS) in transplant patients can arise from donor KS progenitor cells transmitted through the graft, according to Mario Luppi, M.D., Ph.D., assistant professor of hematology, University of Modena and Reggio Emilia.

San Francisco - A one-week course of oral valacyclovir (Valtrex) appears to be a safe, effective, and economical alternative to inpatient or outpatient intravenous (IV) acyclovir (Zovirax) for treatment of immunocompromised patients with uncomplicated, acute herpes zoster virus infections, Mathijs H. Brentjens, M.D., said at the annual meeting of the American Academy of Dermatology.

Dr. Trial has been hired as an expert witness to defend a dermatologist in a medical malpractice case. He rendered his expert opinion stating that he would have performed a dermatologic surgical procedure in a certain manner, even though such an approach was not routinely performed by the dermatologic community. The defendant dermatologist lost the case. His attorney is convinced that the case was lost because Dr. Trial did not perform well on cross-examination. Should Dr. Trial be concerned that he will now be sued?

Increased paperwork is at least partly to blame for many of the management difficulties faced by dermatologists, according to Thomas G. Olsen M.D.

San Francisco - The key to effectively treating toenail and fingernail onychomycosis may lay in the delivery system rather than in the drug itself, according to preliminary results of an open-label feasibility study of a 4 percent clotrimazole lacquer formulated with the drug delivery technology CPE-215 (15 percent).

Maui, Hawaii -- Joseph B. Bikowski, M.D., speaking at the annual Hawaii Dermatology Seminar, offered anecdotal information for 15 common facial issues, based on what has worked in his Pittsburgh-area dermatology practice.

About five years ago, I set up a Web site for my dermatology practice. My Web site was useful not only as a source of information for patients and potential patients but also as a source of information for pharmaceutical companies and other businesses I deal with.

San Francisco -A novel night firming product containing niacinamide, dexpanthenol, tocopherol acetate, and hydrolyzed wheat protein strengthens the stratum corneum better than nine other commercial firming and moisturizing products, according to transepidermal water loss studies performed by Procter & Gamble.

Maui, Hawaii - Canadian physicians in their fifth year of using a hyaluronic acid filler called Restylane can't help but smile -- and neither can their patients.

Orlando - To prevent pressure ulcers in long-term care facilities, clinicians and staff must adopt a multifactorial approach that accounts for everything from diet to patient movement to continence control, according to George Taler, M.D., C.M.D.