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Scottsdale, Ariz. - Medicis Pharmaceutical, based here, has announced that the Food and Drug Administration (FDA) has begun a review of Reloxin, the company’s Botox-like anti-wrinkle injectable, the Arizona Republic reports.

As with any legal or insurance planning, the early bird is richly rewarded. Nowhere in practice planning is this truer than in the Buy-Sell agreement. The reason is not so much economic, but political. If this planning is done before any owner is close to a disability, divorce, retirement, or death, all owners are in the same position relative to each other. That makes the negotiation of a standard deal for all owners a much easier and smoother process. Planning early for a Buy-Sell agreement will truly benefit you, your family and your practice.

A retrospective five-year safety and efficacy study of a new PMMA filler shows a low risk of adverse events and a trend toward continued improvement over the entire five-year follow-up period, says a researcher involved with the study.

Dermatologists commonly turn to a variety of depigmenting agents and therapies for the treatment of melasma and post-inflammatory hyperpigmentation after acne, or traumatic scars and burns, according to Helen M. Torok, M.D., Medical Director, Trillium Creek Dermatology & Surgery, in Medina, Ohio.

A phase 2 study investigated the safety and efficacy of topical bexarotene 1 percent gel (Targretin, Eisai/Ligand) for treating alopecia areata. Hair regrowth of 50 percent or greater was achieved by 26 percent of patients.

Seven newly identified sites of common DNA variations increase the risk for psoriasis and psoriatic arthritis. The whole genome association study of more than 300,000 single nucleotide polymorphisms (SNPs) was published in the March issue of PLoS Genetics. The goal was to identify new genes and new pathways for drug development.

The Food and Drug Administration has been revamping sunscreen safety labeling since the implementation of the final monograph was delayed in 2002. Last August, the FDA issued proposed guidelines for the product labels, with a comment period open until November, 2007. The deadline for comment was extended until late December, and as of May first no new guidelines had been announced.

San Diego - Artes Medical, makers of Artefill, has announded that Douglas Abel, chief executive officer and president of Manhattan Pharmaceuticals, has joined its board of directors, according to Business Wire.

Toronto, Canada - The Dermatology Review Panel (DRP) of Canada has announced three of Pampers babycare products have earned their recommendation and will carry their "Seal of Approval," newswire.ca reports.

Washington - The Associated Press reports that though diagnoses of Merkel cell carcinoma have tripled to about 1,500 a year, there have been no well-controlled studies on the best treatment.

Graz, Austria - Though complete skin examination (CSE) by dermoscopy takes longer to conduct than CSE alone when screening for skin cancer, physicians should consider three-minute screening for the disease with either method, according to the results of a study reported by MedScape Today.

Houston - Data from a large cohort study shows that an elevated level of interleukin-12 is associated with a significantly increased mortality risk in patients with stage III melanoma with regional metastasis, according to MedPageToday.