A poster presentation from Winter Clinical Hawaii evaluated the impact of acne vulgaris on emotional and social functioning among pediatric patients.
To evaluate the symptoms and impact of moderate-to-severe non-nodular acne vulgaris (AV) on emotional functioning, social functioning, and activities of daily living (ADL) among pediatric patients, study authors of a poster presentation from Winter Clinical Hawaii examined AV in community practices across the United States.
The single-arm, prospective cohort study, PROSES (NCT04820673), analyzed patients with moderate-to-severe non-nodular AV ≥9 years who were prescribed sarecycline in real-world US community practices. In total, 300 patients were enrolled from 30 different practices. A validated ASIS questionnaire and an Expert Panel Questionnaire (EPQ) including signs and impact of emotional and social domains were completed by pediatric patients (<12 years) and caregivers (for patients 9-11 years) at baseline and at week 12.
Study results showed that most pediatric patients reported moderate-to-severe AV burden in several areas associated with emotional and physical functioning, and ADL, across the age groups. The EPQ domain questionnaire related to emotional functioning asked the following questions and received the following responses of a moderate-to-severe burden:
The EPQ domain questionnaire related to social functioning asked the following questions and received the following responses of a moderate-to-severe burden:
The EPQ domain questionnaire related to ADL asked the following questions and received the following responses of moderate-to-severe burden:
After reviewing the results, the study authors concluded that “moderate-to-severe AV burden and the psychosocial impact was observed in this prospective cohort of pediatric patients with AV in the US, at the beginning of the PROSES study. Emotional impact and social impact of AV were more pronounced across the pediatric age groups.”