Safety, efficacy of hyaluronic fillers studied

A prospective, open-label Phase 4 study evaluated three low concentration hyaluronic acid fillers for correction of nasolabial folds in 119 persons with skin of color. The results showed clinically significant improvement was achieved and maintained in most patients during follow-up of 24 weeks. No patients experienced permanent pigmentary changes, keloids, hypertrophic scarring, or other significant adverse events.