Opinion|Videos|December 16, 2024
New Systemic Treatments for Prurigo Nodularis
Author(s)Melodie Young, MSN, ANP-C
Key Takeaways
- Prurigo nodularis diagnosis is challenging due to symptom overlap with other pruritic conditions and absence of specific tests.
- Increased prevalence is noted in patients with atopic dermatitis and other specific subtypes.
Melodie Young, MSN, A/GNP-C, discusses how the FDA-approved systemic treatments for prurigo nodularis, dupilumab and nevolizumabnemolizumab, differ in their mechanisms of action—dupilumab targeting IL-4 and IL-13, and nevolizumabnemolizumab targeting IL-31—and highlights their similar efficacy in reducing pruritus and lesion size, while also considering differences in safety profiles and treatment considerations.
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Video content above is prompted by the following:
5. Two systemic treatments are now FDA-approved for prurigo nodularis: dupilumab and nevolizumabnemolizumab. Can you briefly discuss these two 2 agents, including similarities/differences as well as efficacy and safety?
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