A mouse model indicates that a protein-rich diet high in arginine and proline may improve chronic wound healing.
French researchers with Bichat Hospital, Paris, randomly assigned 18 diabetic rats into three dietary groups. One group was fed a standard diet, the second group was fed a high-protein diet, and the third was fed a high-protein diet supplemented with arginine and proline, Medical News Today reports.
The researchers examined full-thickness skin sections, blood sugar, insulin and amino acid concentrations in each rat. The diabetic rats on the high-protein diet with arginine and proline had more new blood vessel growth on day five, and the macrophages showed less cytokine stimulation and pro-inflammatory activity than the other groups, Medical News Today reports.
The study was published online in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology.