
Because BCC and cSCC have high tumor mutational burdens driven by UV-induced DNA damage, they are particularly well suited to immune checkpoint inhibition.

Joshua Burshtein, MD, is a resident physician in the Department of Dermatology at the University of Illinois Chicago.

Because BCC and cSCC have high tumor mutational burdens driven by UV-induced DNA damage, they are particularly well suited to immune checkpoint inhibition.

A phase 2 clinical trial found that topical ruxolitinib cream showed promising efficacy and safety in patients with mild to moderate hidradenitis suppurativa.

IL-17 inhibitors are highly effective, but many patients still require switching due to treatment failure, loss of response, or intolerance.

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