Dermatology Times August 2024 Recap

Clearances, Approvals, Updates, and Recommendations

FDA Approves Denileukin Diftitox for Adults With Relapsed or Refractory Cutaneous T-Cell Lymphoma

The approval is supported by positive phase 3 data for Lymphir in this indication.

FDA Approves Nemolizumab for the Treatment of Prurigo Nodularis

Galderma’s nemolizumab is the first approved monoclonal antibody specifically inhibiting the signaling of IL-31.

FDA Clears Candela's Matrix Radiofrequency Platform for Treatment of Facial Wrinkles

The new indication adds to existing clearances for hemostasis and electrocoagulation.

Big Studies and Big Data

Turn Therapeutics Reports Significant IGA and Cytokine Inhibition, Advances to Plans for In-Human Trial

This article represents the first time the news has been shared with the public. Turn's Founder and CEO, Bradley Burnam, shares details.

Study Finds High Relapse Rate After Discontinuing PsO Biologics

Researchers suggested that early intervention with less than 2 years of disease duration was associated with a lower risk of relapse.

JAK Inhibition With Upadacitinib and Abrocitinib Shows Potential in Rosacea Treatment

Recent research evaluated 6 patients with rosacea treated with JAK1 inhibitors upadacitinib and abrocitinib.

Verrica Announces Positive Preliminary Topline Results From Part 2 of Phase 2 Study of VP-315 for BCC

The overall reduction of tumor size in all lesions treated in part 2 was approximately 86%.

Izokibep Reaches Key Efficacy Endpoints in Phase 3 HS Trial

The trial revealed that 40% of patients on izokibep achieved HiSCR75 by week 16, a notable improvement over the 20% on placebo.

Wearable Sensors Could Revolutionize AD Management

Researchers stated the integration of wearable sensors with AI could potentially revolutionize care for patients with atopic dermatitis.

Higher Risankizumab Adherence with New Injection Device

A recent study found prefilled pens with concealed needles showed promise in reducing injection-related anxiety and improving patient adherence.

GLP-1 Agonists Not Linked to the Development of Acne

Acne vulgaris has been reported as an adverse effect of GLP-1 receptor agonists by some patients.

New Treatment Targets for Atopic Dermatitis

The AHEAD recommendations focus on achieving disease control in atopic dermatitis by allowing patients to identify key symptoms and clinicians to select matching outcomes to guide therapy, aiming for a higher standard of care.

Positive Long-Term Results for Roflumilast Cream in Young Children

Results from the study highlight that the therapy improves AD symptoms over time, with 71.9% of participants achieving substantial improvement.

Market and Pharma News, Drug Watch

“My Skin My Story” Provides Creative Outlet for Young Patients With Eczema

John Browning, MD, FAAD, FAAP, MBA, discusses the new online platform that allows young patients to share their skin journey with others.

Apremilast Now Available for Pediatric Use in the US

The availability is notable as it introduces the first oral treatment option for young psoriasis patients.

Strides for Skin Health Equity

Women With Skin of Color are Underrepresented in Studies of Treatments for Vulvar Lichen Sclerosus

Topical corticosteroids are the gold standard treatment for VLS, yet women with skin of color are not represented in studies.

Navigating the Challenges of Melasma Treatment and Achieving Trial Equity in Melanin-Rich Skin

Melasma, challenging due to varied pigmentation in different skin types, requires personalized, tailored care.

Understanding Dermatological Needs of Gender-Diverse Patients

A recent Australian study reviewed appropriate terminology, gender affirming options, and dermatological considerations in caring for gender-diverse patients.

Chesahna Kindred, MD, MBA, FAAD: Expert Insights on Enhancing Dermatological Care for Patients with Skin of Color

Kindred spoke with Dermatology Times to discuss AbbVie's recent Science of Skin event and improving access to equitable dermatological care.

Understanding the Patient and Advocate Experience: Psoriatic Disease and Skin of Color

Brenda Kong-Tunac, a patient with PsO, PsA, and skin of color, shares her experiences.

Tailoring Aesthetic Treatments for Patients With Skin of Color

Omer Ibrahim, MD, discusses the nuances of aesthetic procedures for patients with skin of color and the importance of tailored treatments, safety, and improved clinician education.

Significant Disparities Persist in Cutaneous Presentations, Diagnosis, and Outcomes of Scleroderma in Skin of Color

In a review, researchers reported that ethnicity plays a role in outcomes, presentations, and more for individuals with systemic sclerosis.

New Toolkit Aims to Boost Diversity in Skin Research

Researchers identified mistrust, social stigma, and language barriers as major obstacles for ethnic minorities in skin research.

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