News

A retrospective study examined the rates of nonmelanoma skin cancer in patients with vitiligo. The data suggest careful surveillance for skin cancer may be prudent in white vitiligo patients.

For patients with stage II melanoma, the adjuvant ganglioside GM2-KLH21 vaccine proved ineffective and possibly even harmful, according to a large, multicenter European study.

The reality is that Mohs surgery can and, at times, does fail. According to one expert, how the surgeon reacts to this challenge in terms of therapy is crucial to the patient's successful outcome.

Incidence reporting data show that melanoma is on the rise, particularly in young women. However, the numbers were calculated using a new method, and the decline may have been an artifact of the new methodology, an expert says.

Treating actinic keratoses early is a must, as these can further develop into squamous cell carcinoma in situ and, in some cases, further complicate in field cancerization patients. Treating these lesions may help to reduce the surge in skin cancers, an expert says.

In a recent study, investigators found that regression alone is an insufficient criterion to validate the use of sentinel lymph node biopsy (SLNB) in patients with thin melanomas.

Because superficial radiotherapy provides safe, effective treatment for many nonmelanoma skin cancers, dermatologists must keep practicing and teaching this discipline rather than ceding it to radiation oncologists, an expert says.

A new sonic brush has demonstrated its safety for use by patients with conditions including rosacea and seborrheic dermatitis, according to several studies. The sonic brush also is safe and effective for removing makeup, and having sonically cleansed skin increases absorption of topical preparations, one of its developers says.

With no randomized, objective studies comparing performance of fractional ablative resurfacing lasers, an expert recommends trying them for oneself before buying.

Incorporating cosmetic dermatology into a medical dermatology practice is made easier if clinicians offer the cosmetic procedures to their existing patients. Internal marketing and a pleasant support staff ensure the success of expansion to cosmetic dermatology.

The full-body skin exam provides an opportunity for dermatologists to broach cosmetic topics of interest to aging baby boomers, an expert says.

As a rule, in order to maintain cosmetic effects from various noninvasive rejuvenation devices currently available on the market, treatments must be repeated. How often these treatments must be repeated is the central issue, and leading noninvasive devices continue to vie for the top spot.

Several novel technologies are emerging for minimally invasive facelifting. According to one expert, the Aptos and now Cousin (elastic ligament knitting) threads lead the way in thread-lifting with a bidirectional cog system, ensuring longer-lasting cosmetic results.

Scar therapy has advanced alongside the development of laser technology. Now, several options exist for various types of scars. Determining the proper treatment for each scar depends on the type of scar being treated.

The advent of fractional resurfacing technologies has raised many controversial questions, an expert says. However, he says what's beyond dispute is that even the most effective resurfacing device works best in the context of combination treatments.

Steps such as taking a biopsy and obtaining a detailed history will assist in making a diagnosis in challenging and unusual cases. In some instances, such as a case of a patient with strongyloidiasis, it may be necessary to perform multiple biopsies to arrive at a diagnosis.

Considering genetics, as well as clinical presentation, will aid in managing challenging cases of skin cancer. It is also incumbent upon clinicians to conduct a comprehensive review of the medical literature to assess the risks associated with metastases of some lesions, such as proliferating trichelemal tumors, according to an expert who treats mainly skin cancer cases.

Despite nearly 20 years of waiting, a difficult case is diagnosed as the rare PAPA syndrome. After treatment with biologic anti-tumor necrosis factor (TNF) drugs, the patient's skin is now clear.

Gastrointestinal (GI) symptoms may sometimes be related to dermatologic conditions. Recognizing the connection can prevent unnecessary complications, an expert says.

Recent studies show that port wine stains (PWSs) are likely to require multiple courses of treatment over a patient's lifetime. Applying topical anti-angiogenic creams may prevent eventual darkening of treated PWSs, an expert says.

A small prospective study suggests oral Lactobacillus could be helpful for patients with atopic dermatitis, although the study's results require validation, a study co-author says.

Even relatively common skin conditions can present themselves in ways that make their diagnosis a bit more challenging than many of the cases dermatologists see every day. Laptop computers resting on the thigh, for example, may lead to erythema ab igne.

With hydroquinone's status in the U.S. marketplace uncertain due to safety concerns, retinoids are increasingly gaining favor in the treatment of postinflammatory hyperpigmentation.

The iPLEDGE program is excellent for protecting the prescriber, so that he or she can continue to practice medicine and responsibly care for patients with severe acne, one dermatologist says. However, the issue of compliance remains a major hurdle.

It's imperative for woundcare specialists to ensure that urine and stool are kept away from the skin. To ensure this, clinicians need to use appropriate barriers. It's also paramount that the barriers be properly removed. If they are not, that can trigger skin damage. Whatever the choice of products used to protect the skin, following structured protocols will keep the integrity of the skin intact.

A double-blind, placebo-controlled dose-ranging study evaluated five dosing regimens of pramiconazole, an oral broad-spectrum triazole antifungal agent, for the treatment of pityriasis versicolor. Four treatment groups demonstrated significant efficacy compared with placebo.

The number of dermatologists who patch test is on the rise for several reasons. Recent innovations aimed at facilitating the ease and speed of patch testing have led to an upswing in its use.

Although dermatologists rarely administer vaccines to prevent skin diseases such as genital HPV, they could be missing an opportunity to help patients avoid these diseases and their consequences, an expert says.

Clinicians should aim to improve the symptom management of malignant wounds, particularly in cases of advanced cancer. One proposed tool to do this is the Toronto Symptom Assessment System for Wounds (TSAS-W). In a pilot study, TSAS-W demonstrated that malignant wounds were the most symptomatic class of wounds.

A recent study shows that the human body produces chemical compounds similar to the active ingredient in marijuana, and these compounds, called endocannabinoids, play an important part in maintaining healthy skin.