The Weekly Roundup: January 5 – 11

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FDA Proposes Mandatory Asbestos Testing for Talc-Containing Cosmetics

The FDA recently proposed a new rule requiring standardized asbestos testing in talc-containing cosmetics to protect consumers from potential harm.

The Impact of Anti-Inflammatory Moisturizers in Mild to Moderate Atopic Dermatitis Treatment

More improved skin hydration and barrier function was observed in moisturizers with anti-inflammatory ingredients, compared to those without.

Quoin Pharmaceuticals’ Announces Positive Interim QRX003 Data for Netherton Syndrome

The results showed promising improvements in all endpoints with high patient satisfaction and no safety concerns.

VYNE Completes Phase 2b Enrollment for Vitiligo Gel

Repibresib’s localized delivery minimizes systemic exposure while targeting inflammatory pathways, a novel approach for vitiligo management.

POLL: Which Anticipated Drug Approval/PDUFA Date Are You Most Looking Forward to in 2025?

Share your insights and anticipation with us.

ART Filler Fine Lines Injections Provide Safe and Long-Term Aesthetic Improvement for Facial Wrinkles

The HA filler with tri-hyal technology reduced wrinkles on the forehead, upper lip, cheek folds, and crow’s feet for up to 18 months.

Introducing Dermatology Times’ 2025 Editor in Chief

Christopher Bunick, MD, PhD, is an associate professor of dermatology and physician-scientist at Yale School of Medicine in New Haven, Connecticut.

Current Evidence is Inadequate in Proving the Benefits of Herbal Remedies on Melasma

With further research, plants such as licorice, tomato, and parsley, could eventually be promising alternatives for melasma patients.

Blisters, Chafing, and More: Common Skin Conditions for Runners

By addressing skin health proactively, runners can enhance performance and longevity in the sport while minimizing discomfort and long-term dermatological damage.

Thinking Outside the Psoriatic Box: Practical Points for Systemic Success

Explore systemic psoriasis management, covering obesity, depression, biologics, and innovative treatment approaches.

Novel Water-Soluble CoQ10 Serum Shows Promising Results for Anti-Aging

The stable preparation combined vitamin C and hyaluronic acid with complexed ubiquinone in this initial study.

The Relationships Between Vitamin D, Zinc, and Seborrheic Dermatitis

While zinc deficiency shows strong ties to SD, researchers stated vitamin D's role is less clear and may depend on genetic factors.

Increased Use of L23.8 Code in Allergic Contact Dermatitis Highlights Need for Specificity in Diagnoses

A Finnish review highlights imprecise use of L23.8 and L23.9 codes for allergic contact dermatitis, impacting data accuracy and patient care.

Unveiling the Complexities of Atopic Dermatitis Care

Experts explore innovative therapies, psychosocial impacts, and education strategies for managing atopic dermatitis in a Dermatology Times video series.

Phase 2 Trial of Qtorin 3.9% Rapamycin Anhydrous Gel Underway in Patients With Cutaneous Venous Malformations

Palvella begins its phase 2 TOIVA trial of Qtorin rapamycin gel for cutaneous venous malformations, targeting the mTOR pathway.

Combination Treatment of Cryolipolysis and Hyaluronic Acid Fillers Greatly Enhances Jawline

The synergistic approach reduced submental fullness, enhanced mandible line definition, and improved chin projection.

Ionic Liquids Boost Skin Drug Delivery

The innovative technology is unlocking new possibilities in dermatology by improving the solubility and permeability of drugs for topical use.

FDA Approves Collagen-Based DermiSphere Hydrogel

Designed to mimic natural tissue scaffolds, DermiSpherehDRT offers innovative support for cellular infiltration and healing in reconstructive surgery.

BioStem Launches BR-AM-DFU Clinical Trial for Non-Healing Diabetic Foot Ulcers

The company is currently recruiting participants to demonstrate the benefits of its BioREtain technology.

UVF Dermoscopy Performs Best Alongside Polarized Light Examination in Scabies Detection

UVF dermoscopy enhances scabies detection, especially in dark skin, with optimal results when combined with polarized light examination.

Next-Gen Therapy: Advancing Topical Therapeutics

Mitragotri said new innovations like ionic liquid-based delivery systems can offer better treatment for immunodermatological conditions.

Fractional Radiofrequency Microneedling is a Safe Monotherapy for Acne Scarring

A recent systemic review found FRM to be an effective treatment modality on its own for managing facial acne scars.

DFD-29: The Journey to FDA Approval and a New Era in Rosacea Management

DFD-29, FDA-approved in 2024, revolutionizes rosacea management by addressing both erythema and inflammatory lesions with a novel extended-release formulation.

ICYMI: Eirion ET-02’s Successful Phase 1 Trial Results for Androgenic Alopecia Treatment

The 5% dosage showed a 6-fold increase in non-vellus hair count after just 5 weeks.

Ruxolitinib Cream Shows Strong Efficacy in Max-Use Pediatric Trial

A study revealed ruxolitinib cream's rapid, lasting benefits in pediatric eczema without systemic safety concerns over a 52-week trial period.

Researchers Develop Recommendations for Hyaluronic Acid Filler Placement in Cases of Hollowness, Volume Deficits

The recommendations place an emphasis on the utility of ultrasound-guided placement to enhance safety.

State-of-the-State Update: Chronic Hand Eczema

Chronic hand eczema poses diagnostic and treatment challenges due to its multifaceted etiology. New therapies like JAK inhibitors offer hope.

Study Reveals Immune Checkpoint Inhibitor Treatment and Monitoring Practices Post-Remission

Post treatment discontinuation, most centers conduct imaging every 3 months during the first year of remission.

Nektar Therapeutics Completes Enrollment for Phase 2b REZOLVE-AD Trial of Rezpegaldesleukin

Rezpegaldesleukin, a novel IL-2 receptor agonist, enters phase 2b evaluation for atopic dermatitis, aiming to advance therapeutic options for this chronic condition.

730-nm Picosecond Laser Can Be Used to Treat Freckles, Novel Study Finds

Patients saw an average clearance rate of 74.46% after just 1 session of laser therapy.

Bridging Therapeutic Innovation and Dermatology

Advancements in therapeutic agents demand innovative strategies for safe, localized skin treatments, Mitragotri argues.

Anti-Wrinkle Cream Containing Horsetail and Soybean is Stable and Efficacious

93.4% of patients saw a positive change in the appearance of forehead wrinkles after 8 weeks of use.

Reflecting on the Growth of NPs and PAs in Dermatology

At the inaugural Horizons in Advanced Practice meeting, Lakshi Aldredge, MSN, ANP-BC, reviewed complex cases on AD and PsO and the role of PAs and NPs in advancing patient care.

Top 5 Articles of the Week: January 5-10

Explore the top headlines of the week including clinical trial updates, FDA announcements, and expert insights.