Opinion|Videos|October 24, 2025

Nonsteroidal Options in Pediatric Atopic Dermatitis

Panelists discuss how they incorporate both steroids and nonsteroidals from the initial visit by limiting steroid use to 1 to 2 weeks followed by long-term nonsteroidal maintenance, while noting the need for more vehicle formulations and lower age indications to better serve younger patients with limited treatment options.

Patients with atopic dermatitis benefit most from comprehensive treatment plans that combine corticosteroids for acute flares and nonsteroidal medications for long-term maintenance, rather than relying solely on traditional short-term steroid cycles. Modern dermatology practice emphasizes limiting topical steroid use to 1 to 2 weeks continuously while transitioning patients to safer nonsteroidal alternatives for ongoing control. This approach minimizes potential adverse effects like stretch marks, steroid withdrawal, and facial acne while providing sustainable disease management that can last for months between flare-ups.

Children and families experience better treatment outcomes when health care providers prescribe both immediate relief options and long-term maintenance therapies during a single visit, eliminating the need for frequent return appointments. The strategy involves using topical steroids to quickly control active inflammation, then switching to nonsteroidal medications that can be used safely for extended periods in areas prone to flaring. This proactive approach empowers families with the tools needed to manage unpredictable flare-ups at home, reducing anxiety and improving overall disease control.

Vehicle formulation preferences vary significantly among patients, particularly those with darker skin tones who may prefer ointments over creams to avoid visible white residue. Although traditional dermatology teaching suggested ointments provide superior medication delivery, newer topical formulations have advanced significantly, offering sophisticated cream bases that provide excellent efficacy without cosmetic concerns. However, patients still need individualized formulation selection, and the limited vehicle options for newer nonsteroidal medications remain a challenge for achieving optimal patient satisfaction and adherence across diverse populations.

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