
EADV 2025: Full Congress Recap
Key Takeaways
- Bimekizumab demonstrated sustained efficacy in psoriasis and hidradenitis suppurativa, maintaining PASI 0 and showing long-term safety.
- Brivekimig and povorcitinib showed promising results in hidradenitis suppurativa, offering new treatment options.
Explore groundbreaking research and insights from the EADV Congress 2025, highlighting advancements in dermatology treatments and patient care.
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Zasocitinib Shows Early DLQI Gains in Patients with Psoriasis
Benefits of zasocitinib on quality of life were observed as early as week 4 and sustained through week 12.
Bimekizumab Sustains PASI 0 in Nearly Half of Patients to Year 4
By blocking 2 key inflammation signals, research found bimekizumab may help keep both skin and joints healthier over time.
Povorcitinib Shows Sustained Efficacy in HS at 24 Weeks
STOP-HS1 and STOP-HS2 phase 3 trials showed nearly 60% of patients achieving HiSCR50 by week 24.
Three-Year Data Reinforce Long-Term Efficacy and Safety of Bimekizumab in Hidradenitis Suppurativa
UCB presented new long-term data demonstrating bimekizumab’s durable efficacy and a consistent safety profile over extended treatment.
Sanofi Announces Positive Phase 2a Results for Brivekimig in HS
Sanofi's brivekimig shows promising phase 2a results for hidradenitis suppurativa, offering hope for effective treatment options.
Celldex Reports Strong Efficacy of Barzolvolimab in Chronic Spontaneous Urticaria Across IgE Subgroups
According to a poster, barzolvolimab achieved comparable improvements in weekly urticaria activity scores across lgE subgroups.
Global Study Links Atopic Eczema to Increased Risk of Suicidal Ideation
A new study links atopic dermatitis to increased suicidal ideation, highlighting the condition's severe psychological impact.
Oral IL-23 Blocker Shows Durable Psoriasis Control at 1 Year
The trial confirmed that icotrokinra’s efficacy is consistent with injectable IL-23 inhibitors while offering an oral option.
Icotrokinra Outperforms Deucravacitinib in Psoriasis Phase 3 Trials
Phase 3 ICONIC-ADVANCE data showed icotrokinra outperformed deucravacitinib in moderate to severe psoriasis.
Ruxolitinib Cream Shows Promise in Prurigo Nodularis at EADV 2025
A meaningful difference in WI-NRS scores was observed as early as day 3 of treatment with ruxolitinib cream.
A Paradigm Shift in Psoriasis Care: Almirall's POSITIVE Study and the Focus on Patient Well-Being
Almirall's POSITIVE study, presented at EADV 2025, prioritizes patient well-being, showcasing the holistic impact of advanced treatments.
Oral TNFR1 Inhibitor Balinatumab Shows Promise in Psoriasis
Balinatumab was generally well tolerated, with common adverse events such as nausea and arthralgia also observed in placebo groups.
OX40 Inhibition Delivers Significant Response in Treatment-Experienced AD
The ROCKET-SHUTTLE trial demonstrates that rocatinlimab, a T-cell rebalancing therapy, significantly improves the signs and symptoms of moderate to severe AD in adults when used with topical therapies.
Galvokimig Achieves High EASI Scores in Pilot Study
Presented at EADV, galvokimig showed promising early results in treating moderate to severe atopic dermatitis, targeting multiple inflammatory pathways for effective relief.
LEO Pharma Presents Late-Breaking Results on Temtokibart for Atopic Dermatitis at EADV
LEO Pharma unveils promising phase 2b trial results for temtokibart, showcasing significant improvements in atopic dermatitis at EADV Congress 2025.
Study Finds Psoriasis Linked to Increased Risk of Age-Related Macular Degeneration
Findings from a large retrospective study presented at EADV 2025 suggest psoriasis significantly increases the risk of both wet and dry age-related macular degeneration.
Peter Lio, MD, at EADV 2025: Rethinking the Atopic Dermatitis Journey
Major unmet needs in pediatric AD include rapid itch relief, access, affordability, and better options for sensitive skin.
Ascletis Presents Positive Phase 3 Data for Denifanstat in Moderate to Severe Acne
Denifanstat shows promising results in treating moderate to severe acne vulgaris, achieving significant efficacy and safety at the EADV Congress 2025.
Guttman-Yassky Showcases 2 Paths to Long-Term AD Control at EADV 2025
At EADV 2025, she showcased how OX40 and JAK inhibition offer complementary approaches to long-term disease control.
KT-621 Shows Strong Phase 1 Results as First-in-Class Oral STAT6 Degrader
The oral degrader produced biomarker reductions consistent with or superior to dupilumab.
Rocatinlimab Maintains Safety Profile in 24-Week AD Study
Together with earlier trials presented at EADV, these findings support OX40 receptor inhibition as a promising therapeutic approach for AD.
DELTA TEEN Trial Demonstrates Superiority of Delgocitinib Cream in Adolescents With Chronic Hand Eczema
Late-breaking EADV 2025 presentations highlighted positive efficacy outcomes in the adolescent population and pooled safety data across 5 phase 2b and phase 3 trials of delgocitinib cream.
Bunick Discusses Dual-Target Biologic at EADV 2025
Galvokamig, a biologic targeting IL-13 and IL-17A/F, demonstrated significant benefits in moderate to severe atopic dermatitis.
APG777 Trial Demonstrates Efficacy, Safety in AD
Treatment with APG777 led to a significant 71.0% reduction in EASI scores from baseline to week 16, compared to a 33.8% reduction with placebo.
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