Dermatology Times January 2025 Recap

Clearances, Approvals, Updates, and Recommendations

FDA Approves Collagen-Based DermiSphere Hydrogel

Designed to mimic natural tissue scaffolds, DermiSphere hDRT offers innovative support for cellular infiltration and healing in reconstructive surgery.

UCB Launches 320mg Single-Injection Bimekizumab

The new dosing option offers convenience for those managing plaque psoriasis, PsA, and hidradenitis suppurativa.

Big Studies and Big Data

Ruxolitinib Cream Shows Strong Efficacy in Max-Use Pediatric Trial

A study revealed ruxolitinib cream's rapid, lasting benefits in pediatric eczema without systemic safety concerns over a 52-week trial period.

High-Risk CSCC Trial Validates Cemiplimab's Potential

Cemiplimab demonstrated a 68% reduction in recurrence risk for high-risk CSCC in the phase 3 C-POST trial, according to Regeneron’s latest findings.

Psoriasis Resolution in a Patient Treated With CD19 CAR T-Cell Therapy for Refractory DLBCL

CD19 CAR T-cell therapy may modulate immune dysregulation in underlying diseases such as psoriasis.

Nutrition, Obesity, and Anxiety Can Impact the Severity of Seborrheic Dermatitis

Investigators found strong correlations between certain eating habits, BMI, psychoemotional status, and SD occurrence.

Secukinumab Demonstrates Long-Term Safety and Efficacy in Pediatric Patients with GPP

In a real-world study, 10 children with generalized pustular psoriasis saw sustained improvements up to 160 weeks.

VP-315 Demonstrates Positive Topline Results in Basal Cell Carcinoma

Three posters supporting VP-315's treatment efficacy and outcomes were presented at the Winter Clinical Miami conference.

Clinical Validation Reached in Phase 2a Trial of AX-158 for Psoriasis

These efficacy results and safety profile confirm what was observed in phase 1 study.

Additional Evidence Supports Quoin’s QRX003 for Netherton Syndrome

QRX003 mimics the LEKTI protein to strengthen skin barriers and alleviate symptoms in patients with Netherton Syndrome.

Nickel is the Most Prevalent Allergen in Pediatric Patients With and Without Atopic Dermatitis

A new review highlights overall allergen rates among children in the United States between 2010 and 2024.

Market and Pharma News, Drug Watch

FDA Proposes Mandatory Asbestos Testing for Talc-Containing Cosmetics

The FDA recently proposed a new rule requiring standardized asbestos testing in talc-containing cosmetics to protect consumers from potential harm.

LEO Pharma and Gilead Will Develop STAT6 Program for AD and Other Inflammatory Diseases

The new partnership will advance the commercialization of small molecule oral STAT6 for patients around the world.

What’s Next for ET-02? CEO of Eirion, Jon Edelson, MD, Shares Phase 2 Plans

“As good as we saw results in 1 month, we think we'll see even more remarkable results over the 6 months of treatment,” Edelson said in an interview with Dermatology Times.

CAGE Bio Advances Skin Disease Treatment

Mitragotri's work bridges advanced drug development and skin care for tailored treatments.

Denise Dajles, DEng, MSc, Ushers in a New Era at Cytrellis Biosystems, Looks to Future of Aesthetics Industry

Cytrellis' new president and CEO discusses bridging surgery and innovation in aesthetics.

First Patient Dosed in Phase 1 Study of Attovia's ATTO-1310 for Chronic Pruritus

Attovia is also advancing 4 ATTOBODY-based programs for inflammatory conditions, such as atopic dermatitis and IBD.

Galderma’s Innovations in Regenerative Aesthetics: Insights from Gerry Muhle

Muhle shares Galderma's study results on Sculptra and Restylane, showcasing regenerative aesthetics and personalized HIT treatments.

Strides for Skin Health Equity

The Intersection of Ethics, Aesthetics, and Patient Expectations in Dermatology

Balancing ethics, aesthetics, and patient expectations is crucial in dermatology to ensure safe, responsible, and ethical care.

Identifying Ancestry-Specific Clinical End Points in Diverse Trials

Researchers are advancing inclusive trials through ancestry-specific endpoints, focusing on skin tone variability, melanin's role, and precision drug modeling.

Novel RF and HIFES Device is Effective for Enhancing Facial Laxity Among Asian Patients

Combining synchronized radiofrequency with high intensity facial electrical stimulation led to firmer, smoother, and more lifted skin.

The Skin Smart Campus Initiative: Promoting Skin Health and Public Awareness at GW

George Washington University recently earned a Skin Smart Campus designation, championing skin cancer prevention through education, free sunscreen, and UV safety measures.

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