
Opinion|Videos|November 28, 2024
Clinical Presentation
Author(s)Andrew F. Alexis, MD, MPH
Key Takeaways
- Segmental vitiligo, typically stable and unilateral, may benefit from surgical interventions, while nonsegmental vitiligo often requires systemic therapies due to its bilateral and progressive nature.
- Patient collaboration is vital in creating treatment plans, focusing on treatment goals, expectations, and potential side effects to ensure personalized care.
Andrew Alexis, MD, MPH, discusses how, in creating individualized treatment plans for vitiligo, clinicians must carefully consider the distinct challenges and response patterns associated with segmental vs nonsegmental forms, as segmental vitiligo tends to be more stable after initial progression but often more resistant to treatment, while nonsegmental vitiligo typically shows a more unpredictable course requiring ongoing management strategies.
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Episodes in this series

Video content above is prompted by the following:
- When you’re coming up with these treatment plans, how do differences in clinical presentation and, progression of segmental and nonsegmental vitiligo influence that plan when you’re creating it? How do you work with a patient to create a treatment plan?
- When you approach segmental vitiligo vs nonsegmental forms, are there any specific challenges associated with each type?
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