Unlocking Skin's Potential from the Inside Out with Glutathione

In a continuing conversation with Dermatology Times, Nayan Patel, PharmD, a compounding pharmacist and the CEO of Auro Skincare, shared his insights into the role of glutathione in dermatologic care. For the past 15 years, Patel has focused on developing technology-driven solutions that enhance glutathione delivery, particularly for skin health. His work addresses oxidative stress, a key contributor to common dermatological issues including pigmentation disorders, collagen degradation, acne, and dermatitis.

Patel emphasized that while dermatologists treat the skin as a visible organ, underlying cellular stress is often overlooked. Oxidative stress disrupts collagen synthesis, damages cellular structures, and impairs the skin’s natural defenses. Glutathione, a naturally occurring antioxidant, plays a central role in mitigating this stress, but its use has been limited due to poor cellular absorption. Patel’s innovation lies in his patented transdermal delivery system, which enables effective topical absorption of glutathione and other synergistic compounds.

His formulation, marketed as a four-product skincare system, includes a glutathione serum, a vitamin C serum, and two complementary moisturizers. This system incorporates antioxidants like CoQ10, carnosine, DMAE, resveratrol, and adaptogens such as cycloastragenol. Together, these agents aim to reduce oxidative stress, allowing the skin—and by extension, the body—to restore homeostasis, improve collagen production, and support immune function.

“If your skin starts getting healthier and looking better and feeling better, you get empowered to heal the rest of the body the same way,” Patel noted.

Patel highlighted the future and broader implications of this technology, which is currently being expanded to deliver peptides such as GHK-Cu, another autologous compound known for skin regeneration. He firmly believes that working with endogenous molecules allows the body to heal itself without the need for synthetic drugs. In closing, Patel encouraged dermatologists to consider glutathione-based interventions as part of their treatment arsenal. He cited the visible, transformative effects in patients globally and positioned his work as a paradigm shift in skin-focused therapies. His book, “The Glutathione Revolution”, chronicles over a decade of research and offers a comprehensive overview of glutathione’s systemic benefits.

“The possibilities of what we can do with this technology when it comes to peptide delivery are going to be something that I'm very excited about,” Patel said. “I get very giddy about it... when I first saw a profound impact in my patients' lives, visibly, it changed the way I looked at medicine.”