Permanent hair dyes cause contact urticaria, anaphylaxis
Palm Beach, Fla. - Paraphenylenediamine, or PPD, the main chemical used in permanent hair dye colors, is the third most common cosmetic allergen, preceded by preservatives (No. 1) and fragrances (No. 2), James S. Taylor, M.D., said at annual meeting of the Noah Worcester Dermatological Society.
The FDA approval, based on 36-week data from the phase 3 BRAVE-AA-PEDS trial, extends baricitinib access to patients as young as 12 years old with severe alopecia areata.
The FDA approved therapies for melanoma, dermatomyositis, superficial basal cell carcinoma, and adolescent alopecia areata, while TYK2 inhibitors and rare disease filings advanced toward 2027 decisions.